Abstract
Two fluorescent substrates for protein tyrosine phosphatase (PTPase) reaction were prepared by conjugation of commercially available O- phosphotyrosine and dansyl chlorides. They were hydrolyzed by CD45 tyrosine phosphatase, and proved to be useful for PTPase assay.
Original language | English |
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Pages (from-to) | 1301-1302 |
Number of pages | 2 |
Journal | Bioorganic and Medicinal Chemistry Letters |
Volume | 8 |
Issue number | 11 |
DOIs | |
Publication status | Published - 1998 Jun 2 |
Keywords
- Amino acids and derivatives
- Enzyme inhibitors
- Fluorescence
ASJC Scopus subject areas
- Biochemistry
- Molecular Medicine
- Molecular Biology
- Pharmaceutical Science
- Drug Discovery
- Clinical Biochemistry
- Organic Chemistry