Synthesis of hipposudoric and norhipposudoric acids: The pigments responsible for the color reaction of the red sweat of Hippopotamus amphibius

Yoko Saikawa, Kai Moriya, Kimiko Hashimoto, Masaya Nakata

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Highly unstable pigments, hipposudoric acid and norhipposudoric acid, isolated from the red sweat of hippopotamus were synthesized using the Pschorr reaction for the construction of the fluorene nucleus as the key step and the careful oxidation in the last step.

Original languageEnglish
Pages (from-to)2535-2538
Number of pages4
JournalTetrahedron Letters
Issue number15
Publication statusPublished - 2006 Apr 10



  • Fluorene
  • Hippopotamus amphibius
  • Hipposudoric acid
  • Norhipposudoric acid
  • Pschorr reaction

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

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