Synthesis of immunoregulatory Helicobacter pylori lipopolysaccharide partial structures

Yukari Fujimoto, Masato Iwata, Noriko Imakita, Atsushi Shimoyama, Yasuo Suda, Shoichi Kusumoto, Koichi Fukase

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25 Citations (Scopus)

Abstract

The synthesis of immunoregulatory glycoconjugates, namely the active entity of lipopolysaccharide (LPS) from Helicobacter pylori was achieved. The results of biological activities of the LPS partial structures provide the structural basis for the immunobiological activity, especially for the immune inhibitory activity of H. pylori LPS.

Original languageEnglish
Pages (from-to)6577-6581
Number of pages5
JournalTetrahedron Letters
Volume48
Issue number37
DOIs
Publication statusPublished - 2007 Sep 10

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ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Cite this

Fujimoto, Y., Iwata, M., Imakita, N., Shimoyama, A., Suda, Y., Kusumoto, S., & Fukase, K. (2007). Synthesis of immunoregulatory Helicobacter pylori lipopolysaccharide partial structures. Tetrahedron Letters, 48(37), 6577-6581. https://doi.org/10.1016/j.tetlet.2007.07.036