Synthesis of immunoregulatory Helicobacter pylori lipopolysaccharide partial structures

Yukari Fujimoto, Masato Iwata, Noriko Imakita, Atsushi Shimoyama, Yasuo Suda, Shoichi Kusumoto, Koichi Fukase

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

The synthesis of immunoregulatory glycoconjugates, namely the active entity of lipopolysaccharide (LPS) from Helicobacter pylori was achieved. The results of biological activities of the LPS partial structures provide the structural basis for the immunobiological activity, especially for the immune inhibitory activity of H. pylori LPS.

Original languageEnglish
Pages (from-to)6577-6581
Number of pages5
JournalTetrahedron Letters
Volume48
Issue number37
DOIs
Publication statusPublished - 2007 Sep 10
Externally publishedYes

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Lipopolysaccharides
Glycoconjugates
Bioactivity
Helicobacter pylori lipopolysaccharide

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Fujimoto, Y., Iwata, M., Imakita, N., Shimoyama, A., Suda, Y., Kusumoto, S., & Fukase, K. (2007). Synthesis of immunoregulatory Helicobacter pylori lipopolysaccharide partial structures. Tetrahedron Letters, 48(37), 6577-6581. https://doi.org/10.1016/j.tetlet.2007.07.036

Synthesis of immunoregulatory Helicobacter pylori lipopolysaccharide partial structures. / Fujimoto, Yukari; Iwata, Masato; Imakita, Noriko; Shimoyama, Atsushi; Suda, Yasuo; Kusumoto, Shoichi; Fukase, Koichi.

In: Tetrahedron Letters, Vol. 48, No. 37, 10.09.2007, p. 6577-6581.

Research output: Contribution to journalArticle

Fujimoto, Y, Iwata, M, Imakita, N, Shimoyama, A, Suda, Y, Kusumoto, S & Fukase, K 2007, 'Synthesis of immunoregulatory Helicobacter pylori lipopolysaccharide partial structures', Tetrahedron Letters, vol. 48, no. 37, pp. 6577-6581. https://doi.org/10.1016/j.tetlet.2007.07.036
Fujimoto, Yukari ; Iwata, Masato ; Imakita, Noriko ; Shimoyama, Atsushi ; Suda, Yasuo ; Kusumoto, Shoichi ; Fukase, Koichi. / Synthesis of immunoregulatory Helicobacter pylori lipopolysaccharide partial structures. In: Tetrahedron Letters. 2007 ; Vol. 48, No. 37. pp. 6577-6581.
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