Synthesis of methylophiopogonanone a

Research output: Contribution to journalArticlepeer-review

Abstract

Ophiopogon Root (root of Ophiopogon japonicus Ker-Gawler, Liliaceae) is a crude drug used as expectorant, anti-cough and tonic in Kampo medicine (traditional Japanese medicine) as well as other traditional medicines of Asian countries. It contains characteristic homoisoflavonoids with methylated ring A. We synthesized methylophiopogonanone A (1), which is a candidate marker compound for identification test of Ophiopogon Root, from phloroglucinol in 9 steps with overall yield of 11.1%.

Original languageEnglish
Pages (from-to)803-808
Number of pages6
JournalHeterocycles
Volume100
Issue number5
DOIs
Publication statusPublished - 2020

ASJC Scopus subject areas

  • Analytical Chemistry
  • Pharmacology
  • Organic Chemistry

Fingerprint Dive into the research topics of 'Synthesis of methylophiopogonanone a'. Together they form a unique fingerprint.

Cite this