Synthesis of model compounds related to linear β-d-(1→6)-galactosyl side-chains of polysaccharides from astragalus mongholicus bunge

Noriyasu Hada, Ryo Shimura, Kyoko Hakamata, Hiroaki Kiyohara, Haruki Yamada, Adahiro Takeda, Fumiyuki Kiuchi

Research output: Contribution to journalArticle

Abstract

Stereocontrolled efficient syntheses of β-d-(1→6)-linked di-, tetra- and octa-galactans as model compounds of arabino-3,6-galactans isolated from Astragalus mongholicus are described. The syntheses consisted of simple glycosylation cycles: an acceptor and a donor prepared from a common compound were coupled, and the glycosylation product was converted to the acceptor and donor of the next glycosylation.

Original languageEnglish
Pages (from-to)563-578
Number of pages16
JournalHeterocycles
Volume90
Issue number1
DOIs
Publication statusPublished - 2015

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Galactans
Glycosylation
Polysaccharides

ASJC Scopus subject areas

  • Analytical Chemistry
  • Organic Chemistry
  • Pharmacology

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Synthesis of model compounds related to linear β-d-(1→6)-galactosyl side-chains of polysaccharides from astragalus mongholicus bunge. / Hada, Noriyasu; Shimura, Ryo; Hakamata, Kyoko; Kiyohara, Hiroaki; Yamada, Haruki; Takeda, Adahiro; Kiuchi, Fumiyuki.

In: Heterocycles, Vol. 90, No. 1, 2015, p. 563-578.

Research output: Contribution to journalArticle

Hada, Noriyasu ; Shimura, Ryo ; Hakamata, Kyoko ; Kiyohara, Hiroaki ; Yamada, Haruki ; Takeda, Adahiro ; Kiuchi, Fumiyuki. / Synthesis of model compounds related to linear β-d-(1→6)-galactosyl side-chains of polysaccharides from astragalus mongholicus bunge. In: Heterocycles. 2015 ; Vol. 90, No. 1. pp. 563-578.
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