Synthesis of okicamelliaside, a glucoside of ellagic acid with potent anti-degranulation activity

Ryohei Kobayashi, Kengo Hanaya, Mitsuru Shoji, Shigeru Ohba, Takeshi Sugai

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Okicamelliaside, a glucoside of ellagic acid with potent anti-degranulation activity, was synthesized from ellagic acid. The regioselectivity, solubility, and high reactivity of the intermediates throughout the synthesis were obtained by the complementary use of triisopropylsilyl (TIPS) and methoxyethoxymethyl (MEM) protective groups on the aglycone skeleton.

Original languageEnglish
Pages (from-to)810-813
Number of pages4
JournalBioscience, Biotechnology and Biochemistry
Volume77
Issue number4
DOIs
Publication statusPublished - 2013

Fingerprint

Ellagic Acid
Glucosides
Regioselectivity
Skeleton
Solubility
okicamelliaside

Keywords

  • Ellagic acid
  • Glucoside
  • Okicamelliaside

ASJC Scopus subject areas

  • Biotechnology
  • Biochemistry
  • Molecular Biology
  • Applied Microbiology and Biotechnology
  • Analytical Chemistry
  • Organic Chemistry

Cite this

Synthesis of okicamelliaside, a glucoside of ellagic acid with potent anti-degranulation activity. / Kobayashi, Ryohei; Hanaya, Kengo; Shoji, Mitsuru; Ohba, Shigeru; Sugai, Takeshi.

In: Bioscience, Biotechnology and Biochemistry, Vol. 77, No. 4, 2013, p. 810-813.

Research output: Contribution to journalArticle

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AU - Sugai, Takeshi

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