Synthesis of palau'amide and its diastereomers: confirmation of its stereostructure

Hirokazu Sugiyama, Atsushi Watanabe, Toshiaki Teruya, Kiyotake Suenaga

Research output: Contribution to journalArticlepeer-review

15 Citations (Scopus)

Abstract

Four diastereomers of palau'amide (1-4), a cytotoxic cyclodepsipeptide, were synthesized. The 1H NMR spectrum of 1 was identical to that of natural palau'amide. This established the complete stereostructure of palau'amide.

Original languageEnglish
Pages (from-to)7343-7345
Number of pages3
JournalTetrahedron Letters
Volume50
Issue number52
DOIs
Publication statusPublished - 2009 Dec 30

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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