TY - JOUR
T1 - Synthesis of practical red fluorescent probe for cytoplasmic calcium ions with greatly improved cell-membrane permeability
AU - Hirabayashi, Kazuhisa
AU - Hanaoka, Kenjiro
AU - Egawa, Takahiro
AU - Kobayashi, Chiaki
AU - Takahashi, Shodai
AU - Komatsu, Toru
AU - Ueno, Tasuku
AU - Terai, Takuya
AU - Ikegaya, Yuji
AU - Nagano, Tetsuo
AU - Urano, Yasuteru
N1 - Funding Information:
This work was supported in parts by MEXT (Specially Promoted Research Grant Nos. 22000006 to T.N., Grant Nos. 24689003, 24659042 and 26104509 to K.Hanaoka, and Grant Nos. 24655147 to T.K.), and SENTAN, JST to K.Hanaoka. K.Hanaoka was also supported by Mochida Memorial Foundation for Medical and Pharmaceutical Research, The Asahi Glass Foundation, Takeda Science Foundation and The Cosmetology Research Foundation. K.Hirabayashi was supported by a Grant-in-Aid for JSPS Fellows.
Publisher Copyright:
© 2017 The Authors
PY - 2017/6/1
Y1 - 2017/6/1
N2 - In this data article, we described the detailed synthetic procedure and the experimental data for the synthesis of a red-fluorescent probe for calcium ions (Ca2+) with improved water solubility. This Ca2+ red-fluorescent probe CaTM-3 AM could be applied to fluorescence imaging of physiological Ca2+ concentration changes in not only live cells, but also brain slices, with high cell-membrane permeability leading to bright fluorescence in biosamples. The data provided herein are in association with the research article “The Development of Practical Red Fluorescent Probe for Cytoplasmic Calcium Ions with Greatly Improved Cell-membrane Permeability” in Cell Calcium (Hirabayashi et al., 2016) [1].
AB - In this data article, we described the detailed synthetic procedure and the experimental data for the synthesis of a red-fluorescent probe for calcium ions (Ca2+) with improved water solubility. This Ca2+ red-fluorescent probe CaTM-3 AM could be applied to fluorescence imaging of physiological Ca2+ concentration changes in not only live cells, but also brain slices, with high cell-membrane permeability leading to bright fluorescence in biosamples. The data provided herein are in association with the research article “The Development of Practical Red Fluorescent Probe for Cytoplasmic Calcium Ions with Greatly Improved Cell-membrane Permeability” in Cell Calcium (Hirabayashi et al., 2016) [1].
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U2 - 10.1016/j.dib.2017.04.011
DO - 10.1016/j.dib.2017.04.011
M3 - Article
AN - SCOPUS:85018926822
SN - 2352-3409
VL - 12
SP - 351
EP - 357
JO - Data in Brief
JF - Data in Brief
ER -