Synthesis of the C15-C27 portion of venturicidins: A formal total synthesis of venturicidin X

Keiji Tsunashima, Mitsuaki Ide, Hiroshi Kadoi, Aya Hirayama, Masaya Nakata

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

The C15-C27 portion of venturicidin X was prepared using substitution reactions of alkyl trifluoromethanesulfonates with a vinylmetal compound followed by homogeneous hydrogenation. Together with our previous synthesis of the C1-C14 portion of venturicidin X, a formal total synthesis of venturicidin X was completed.

Original languageEnglish
Pages (from-to)3607-3611
Number of pages5
JournalTetrahedron Letters
Volume42
Issue number21
DOIs
Publication statusPublished - 2001 May 21

Fingerprint

Hydrogenation
Substitution reactions
venturicidin A
venturicidin
trifluoromethanesulfonic acid

Keywords

  • Hydrogenation
  • Substitution
  • Two-stage coupling process
  • Venturicidins

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Synthesis of the C15-C27 portion of venturicidins : A formal total synthesis of venturicidin X. / Tsunashima, Keiji; Ide, Mitsuaki; Kadoi, Hiroshi; Hirayama, Aya; Nakata, Masaya.

In: Tetrahedron Letters, Vol. 42, No. 21, 21.05.2001, p. 3607-3611.

Research output: Contribution to journalArticle

Tsunashima, Keiji ; Ide, Mitsuaki ; Kadoi, Hiroshi ; Hirayama, Aya ; Nakata, Masaya. / Synthesis of the C15-C27 portion of venturicidins : A formal total synthesis of venturicidin X. In: Tetrahedron Letters. 2001 ; Vol. 42, No. 21. pp. 3607-3611.
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