Synthesis of the c15-c27 portion of venturicidins: A formal total synthesis of venturicidin x

Keiji Tsunashima; Mitsuaki Ide; Hiroshi Kadoi; Aya Hirayama; Masaya Nakata

doi:10.1016/S0040-4039(01)00518-4

Synthesis of the c15-c27 portion of venturicidins: A formal total synthesis of venturicidin x

Keiji Tsunashima, Mitsuaki Ide, Hiroshi Kadoi, Aya Hirayama, Masaya Nakata

Department of Applied Chemistry

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

The C15-C27 portion of venturicidin X was prepared using substitution reactions of alkyl trifluoromethanesulfonates with a vinylmetal compound followed by homogeneous hydrogenation. Together with our previous synthesis of the C1-C14 portion of venturicidin X, a formal total synthesis of venturicidin X was completed.

Original language	English
Pages (from-to)	3607-3611
Number of pages	5
Journal	Tetrahedron Letters
Volume	42
Issue number	21
DOIs	https://doi.org/10.1016/S0040-4039(01)00518-4
Publication status	Published - 2001 May 21

Keywords

Hydrogenation
Substitution
Two-stage coupling process
Venturicidins

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/S0040-4039(01)00518-4

Cite this

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abstract = "The C15-C27 portion of venturicidin X was prepared using substitution reactions of alkyl trifluoromethanesulfonates with a vinylmetal compound followed by homogeneous hydrogenation. Together with our previous synthesis of the C1-C14 portion of venturicidin X, a formal total synthesis of venturicidin X was completed.",

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T2 - A formal total synthesis of venturicidin x

AU - Tsunashima, Keiji

AU - Ide, Mitsuaki

AU - Kadoi, Hiroshi

AU - Hirayama, Aya

AU - Nakata, Masaya

PY - 2001/5/21

Y1 - 2001/5/21

N2 - The C15-C27 portion of venturicidin X was prepared using substitution reactions of alkyl trifluoromethanesulfonates with a vinylmetal compound followed by homogeneous hydrogenation. Together with our previous synthesis of the C1-C14 portion of venturicidin X, a formal total synthesis of venturicidin X was completed.

AB - The C15-C27 portion of venturicidin X was prepared using substitution reactions of alkyl trifluoromethanesulfonates with a vinylmetal compound followed by homogeneous hydrogenation. Together with our previous synthesis of the C1-C14 portion of venturicidin X, a formal total synthesis of venturicidin X was completed.

KW - Hydrogenation

KW - Substitution

KW - Two-stage coupling process

KW - Venturicidins

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U2 - 10.1016/S0040-4039(01)00518-4

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JO - Tetrahedron Letters

JF - Tetrahedron Letters

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ER -

Synthesis of the c15-c27 portion of venturicidins: A formal total synthesis of venturicidin x

Abstract

Keywords

ASJC Scopus subject areas

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