Synthesis of the C17-C27 fragment of bryostatin 3

Tetsuo Obitsu, Ken Ohmori, Yasuyuki Ogawa, Hiroyuki Hosomi, Shigeru Ohba, Shigeru Nishiyama, Shosuke Yamamura

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

The key synthetic intermediate corresponding to the C17 - C27 positions of bryostatin 3, has successfully been synthesized. The newly constructed stereogenic centers were unambiguously confirmed by X-ray crystallographic analysis.

Original languageEnglish
Pages (from-to)7349-7352
Number of pages4
JournalTetrahedron Letters
Volume39
Issue number40
Publication statusPublished - 1998 Oct 1

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X-Rays
X rays
bryostatin 3

Keywords

  • Biologically active compounds
  • Macrolides
  • Marine metabolites
  • Polyketides

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Obitsu, T., Ohmori, K., Ogawa, Y., Hosomi, H., Ohba, S., Nishiyama, S., & Yamamura, S. (1998). Synthesis of the C17-C27 fragment of bryostatin 3. Tetrahedron Letters, 39(40), 7349-7352.

Synthesis of the C17-C27 fragment of bryostatin 3. / Obitsu, Tetsuo; Ohmori, Ken; Ogawa, Yasuyuki; Hosomi, Hiroyuki; Ohba, Shigeru; Nishiyama, Shigeru; Yamamura, Shosuke.

In: Tetrahedron Letters, Vol. 39, No. 40, 01.10.1998, p. 7349-7352.

Research output: Contribution to journalArticle

Obitsu, T, Ohmori, K, Ogawa, Y, Hosomi, H, Ohba, S, Nishiyama, S & Yamamura, S 1998, 'Synthesis of the C17-C27 fragment of bryostatin 3', Tetrahedron Letters, vol. 39, no. 40, pp. 7349-7352.
Obitsu T, Ohmori K, Ogawa Y, Hosomi H, Ohba S, Nishiyama S et al. Synthesis of the C17-C27 fragment of bryostatin 3. Tetrahedron Letters. 1998 Oct 1;39(40):7349-7352.
Obitsu, Tetsuo ; Ohmori, Ken ; Ogawa, Yasuyuki ; Hosomi, Hiroyuki ; Ohba, Shigeru ; Nishiyama, Shigeru ; Yamamura, Shosuke. / Synthesis of the C17-C27 fragment of bryostatin 3. In: Tetrahedron Letters. 1998 ; Vol. 39, No. 40. pp. 7349-7352.
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