Synthesis of the C17-C27 fragment of bryostatin 3

Tetsuo Obitsu; Ken Ohmori; Yasuyuki Ogawa; Hiroyuki Hosomi; Shigeru Ohba; Shigeru Nishiyama; Shosuke Yamamura

doi:10.1016/S0040-4039(98)01577-9

Synthesis of the C₁₇-C₂₇ fragment of bryostatin 3

Tetsuo Obitsu, Ken Ohmori, Yasuyuki Ogawa, Hiroyuki Hosomi, Shigeru Ohba, Shigeru Nishiyama, Shosuke Yamamura

Department of Humanities and Social Sciences

Research output: Contribution to journal › Article › peer-review

22 Citations (Scopus)

Abstract

The key synthetic intermediate corresponding to the C17 - C27 positions of bryostatin 3, has successfully been synthesized. The newly constructed stereogenic centers were unambiguously confirmed by X-ray crystallographic analysis.

Original language	English
Pages (from-to)	7349-7352
Number of pages	4
Journal	Tetrahedron Letters
Volume	39
Issue number	40
DOIs	https://doi.org/10.1016/S0040-4039(98)01577-9
Publication status	Published - 1998 Oct 1

Keywords

Biologically active compounds
Macrolides
Marine metabolites
Polyketides

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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title = "Synthesis of the C17-C27 fragment of bryostatin 3",

abstract = "The key synthetic intermediate corresponding to the C17 - C27 positions of bryostatin 3, has successfully been synthesized. The newly constructed stereogenic centers were unambiguously confirmed by X-ray crystallographic analysis.",

keywords = "Biologically active compounds, Macrolides, Marine metabolites, Polyketides",

author = "Tetsuo Obitsu and Ken Ohmori and Yasuyuki Ogawa and Hiroyuki Hosomi and Shigeru Ohba and Shigeru Nishiyama and Shosuke Yamamura",

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T1 - Synthesis of the C17-C27 fragment of bryostatin 3

AU - Obitsu, Tetsuo

AU - Ohmori, Ken

AU - Ogawa, Yasuyuki

AU - Hosomi, Hiroyuki

AU - Ohba, Shigeru

AU - Nishiyama, Shigeru

AU - Yamamura, Shosuke

PY - 1998/10/1

Y1 - 1998/10/1

N2 - The key synthetic intermediate corresponding to the C17 - C27 positions of bryostatin 3, has successfully been synthesized. The newly constructed stereogenic centers were unambiguously confirmed by X-ray crystallographic analysis.

AB - The key synthetic intermediate corresponding to the C17 - C27 positions of bryostatin 3, has successfully been synthesized. The newly constructed stereogenic centers were unambiguously confirmed by X-ray crystallographic analysis.

KW - Biologically active compounds

KW - Macrolides

KW - Marine metabolites

KW - Polyketides

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JO - Tetrahedron Letters

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