Synthesis of the novel analogues of dysidiolide and their structure-activity relationship

Masato Takahashi, Kosuke Dodo, Yoshikazu Sugimoto, Yoshimi Aoyagi, Yuji Yamada, Yuichi Hashimoto, Ryuichi Shirai

Research output: Contribution to journalArticle

58 Citations (Scopus)

Abstract

The novel analogues of natural cdc25A inhibitor dysidiolide were synthesized. To investigate the structure-activity relationship, the inhibitory activity to enzyme and cell cycle was examined. (C) 2000 Elsevier Science Ltd.

Original languageEnglish
Pages (from-to)2571-2574
Number of pages4
JournalBioorganic and Medicinal Chemistry Letters
Volume10
Issue number22
DOIs
Publication statusPublished - 2000 Nov 20
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmaceutical Science
  • Drug Discovery
  • Clinical Biochemistry
  • Organic Chemistry

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