Synthesis of the novel analogues of dysidiolide and their structure-activity relationship

Masato Takahashi; Kosuke Dodo; Yoshikazu Sugimoto; Yoshimi Aoyagi; Yuji Yamada; Yuichi Hashimoto; Ryuichi Shirai

doi:10.1016/S0960-894X(00)00527-8

Synthesis of the novel analogues of dysidiolide and their structure-activity relationship

Masato Takahashi, Kosuke Dodo, Yoshikazu Sugimoto, Yoshimi Aoyagi, Yuji Yamada, Yuichi Hashimoto, Ryuichi Shirai

Research output: Contribution to journal › Article › peer-review

15 Citations (Scopus)

Abstract

The novel analogues of natural cdc25A inhibitor dysidiolide were synthesized. To investigate the structure-activity relationship, the inhibitory activity to enzyme and cell cycle was examined. (C) 2000 Elsevier Science Ltd.

Original language	English
Pages (from-to)	2571-2574
Number of pages	4
Journal	Bioorganic and Medicinal Chemistry Letters
Volume	10
Issue number	22
DOIs	https://doi.org/10.1016/S0960-894X(00)00527-8
Publication status	Published - 2000 Nov 20
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Molecular Medicine
Molecular Biology
Pharmaceutical Science
Drug Discovery
Clinical Biochemistry
Organic Chemistry

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10.1016/S0960-894X(00)00527-8

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title = "Synthesis of the novel analogues of dysidiolide and their structure-activity relationship",

abstract = "The novel analogues of natural cdc25A inhibitor dysidiolide were synthesized. To investigate the structure-activity relationship, the inhibitory activity to enzyme and cell cycle was examined. (C) 2000 Elsevier Science Ltd.",

author = "Masato Takahashi and Kosuke Dodo and Yoshikazu Sugimoto and Yoshimi Aoyagi and Yuji Yamada and Yuichi Hashimoto and Ryuichi Shirai",

note = "Funding Information: This work was supported in part by a Grant-in-Aid for Scientific Research from the Ministry of Education, Science, Sports and Culture, Japan.",

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T1 - Synthesis of the novel analogues of dysidiolide and their structure-activity relationship

AU - Takahashi, Masato

AU - Dodo, Kosuke

AU - Sugimoto, Yoshikazu

AU - Aoyagi, Yoshimi

AU - Yamada, Yuji

AU - Hashimoto, Yuichi

AU - Shirai, Ryuichi

N1 - Funding Information: This work was supported in part by a Grant-in-Aid for Scientific Research from the Ministry of Education, Science, Sports and Culture, Japan.

PY - 2000/11/20

Y1 - 2000/11/20

N2 - The novel analogues of natural cdc25A inhibitor dysidiolide were synthesized. To investigate the structure-activity relationship, the inhibitory activity to enzyme and cell cycle was examined. (C) 2000 Elsevier Science Ltd.

AB - The novel analogues of natural cdc25A inhibitor dysidiolide were synthesized. To investigate the structure-activity relationship, the inhibitory activity to enzyme and cell cycle was examined. (C) 2000 Elsevier Science Ltd.

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U2 - 10.1016/S0960-894X(00)00527-8

DO - 10.1016/S0960-894X(00)00527-8

M3 - Article

C2 - 11086732

AN - SCOPUS:0034694356

SN - 0960-894X

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JO - Bioorganic and Medicinal Chemistry Letters

JF - Bioorganic and Medicinal Chemistry Letters

IS - 22

ER -

Synthesis of the novel analogues of dysidiolide and their structure-activity relationship

Abstract

ASJC Scopus subject areas

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