Synthesis of the racemic and optically active forms of gizzerosine, the inducer of gizzard erosion in chicks

Kenji Mori; Takeshi Sugai; Yukari Maeda; Tomomi Okazaki; Tadashi Noguchi; Hiroshi Naito

doi:10.1016/S0040-4020(01)96782-1

Synthesis of the racemic and optically active forms of gizzerosine, the inducer of gizzard erosion in chicks

Kenji Mori, Takeshi Sugai, Yukari Maeda, Tomomi Okazaki, Tadashi Noguchi, Hiroshi Naito

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

The racemate and both the (R)- and (S)-forms of gizzerosine [2-amino-9-(4-imidazolyl)-7-azanonanoic acid] were synthesised, and the (S)-isomer was identified as the toxic substance in fish meal causing severe gizzard erosion (black vomit) in chicks.

Original language	English
Pages (from-to)	5307-5311
Number of pages	5
Journal	Tetrahedron
Volume	41
Issue number	22
DOIs	https://doi.org/10.1016/S0040-4020(01)96782-1
Publication status	Published - 1985
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/S0040-4020(01)96782-1

Cite this

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abstract = "The racemate and both the (R)- and (S)-forms of gizzerosine [2-amino-9-(4-imidazolyl)-7-azanonanoic acid] were synthesised, and the (S)-isomer was identified as the toxic substance in fish meal causing severe gizzard erosion (black vomit) in chicks.",

author = "Kenji Mori and Takeshi Sugai and Yukari Maeda and Tomomi Okazaki and Tadashi Noguchi and Hiroshi Naito",

year = "1985",

doi = "10.1016/S0040-4020(01)96782-1",

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T1 - Synthesis of the racemic and optically active forms of gizzerosine, the inducer of gizzard erosion in chicks

AU - Mori, Kenji

AU - Sugai, Takeshi

AU - Maeda, Yukari

AU - Okazaki, Tomomi

AU - Noguchi, Tadashi

AU - Naito, Hiroshi

PY - 1985

Y1 - 1985

N2 - The racemate and both the (R)- and (S)-forms of gizzerosine [2-amino-9-(4-imidazolyl)-7-azanonanoic acid] were synthesised, and the (S)-isomer was identified as the toxic substance in fish meal causing severe gizzard erosion (black vomit) in chicks.

AB - The racemate and both the (R)- and (S)-forms of gizzerosine [2-amino-9-(4-imidazolyl)-7-azanonanoic acid] were synthesised, and the (S)-isomer was identified as the toxic substance in fish meal causing severe gizzard erosion (black vomit) in chicks.

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DO - 10.1016/S0040-4020(01)96782-1

M3 - Article

AN - SCOPUS:0009938718

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JO - Tetrahedron

JF - Tetrahedron

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ER -

Synthesis of the racemic and optically active forms of gizzerosine, the inducer of gizzard erosion in chicks

Abstract

ASJC Scopus subject areas

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