Synthesis of the racemic and optically active forms of gizzerosine, the inducer of gizzard erosion in chicks

Kenji Mori, Takeshi Sugai, Yukari Maeda, Tomomi Okazaki, Tadashi Noguchi, Hiroshi Naito

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

The racemate and both the (R)- and (S)-forms of gizzerosine [2-amino-9-(4-imidazolyl)-7-azanonanoic acid] were synthesised, and the (S)-isomer was identified as the toxic substance in fish meal causing severe gizzard erosion (black vomit) in chicks.

Original languageEnglish
Pages (from-to)5307-5311
Number of pages5
JournalTetrahedron
Volume41
Issue number22
DOIs
Publication statusPublished - 1985
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Fingerprint Dive into the research topics of 'Synthesis of the racemic and optically active forms of gizzerosine, the inducer of gizzard erosion in chicks'. Together they form a unique fingerprint.

  • Cite this