Synthesis of Thermoplastic Poly(2-methoxyethyl acrylate)-Based Polyurethane by RAFT and Condensation Polymerization

Shunsuke Tazawa, Tomoki Maeda, Masamitsu Nakayama, Atsushi Hotta

Research output: Contribution to journalArticle

Abstract

Thermoplastic solid poly(2-methoxyethyl acrylate) (PMEA)-based polyurethane (PU) is synthesized through the reversible addition−fragmentation chain transfer (RAFT) polymerization and the condensation polymerization, using hydroxyl-terminated RAFT reagents and diisocyanate, respectively. Neat PMEA is a promising antithrombogenic liquid used in the medical fields. The thermoplastic property of the solid PMEA-based PU due to hydrogen bonding is confirmed by the dynamic mechanical analysis (DMA) at temperature below 72 °C. The antithrombogenic property of PMEA-based PU is also analyzed by the platelet adhesion test. The number of platelets on PMEA-based PU is 17 cells per unit area, which is smaller than that on the fluorinated diamond-like carbon (F-DLC), a well-known highly antithrombogenic material. It is concluded that a newly synthesized PMEA-based PU exhibits thermoplastic characteristics with excellent antithrombogenicity.

Original languageEnglish
JournalMacromolecular Rapid Communications
DOIs
Publication statusAccepted/In press - 2020

Keywords

  • PMEA
  • antithrombogenicity
  • hydrogen bonding
  • polymerizations
  • thermoplastics

ASJC Scopus subject areas

  • Organic Chemistry
  • Polymers and Plastics
  • Materials Chemistry

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