Abstract
Trilobatin [4-(β-D-glucopyranosyloxy)-2,4”,6-trihydroxydihydrochalcone] was synthesized from commercially available naringin in three steps with an overall yield of 30%. The key step was the acid-catalyzed site-selective hydrolysis of terminal α-rhamnopyranosidic linkage in neohesperidose involved in naringin under controlled conditions, by applying a high-pressure steam sterilizer.
Original language | English |
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Pages (from-to) | 1463-1467 |
Number of pages | 5 |
Journal | Bioscience, Biotechnology and Biochemistry |
Volume | 82 |
Issue number | 9 |
DOIs | |
Publication status | Published - 2018 |
Keywords
- Dihydrochalcone glycoside
- Naringin
- Site-selective hydrolysis
- Trilobatin
ASJC Scopus subject areas
- Biotechnology
- Analytical Chemistry
- Biochemistry
- Applied Microbiology and Biotechnology
- Molecular Biology
- Organic Chemistry