Synthesis of various water-soluble C60 derivatives and their superoxide-quenching activity

Kensuke Okuda, Takashi Hirota, Masaaki Hirobe, Tetsuo Nagano, Masataka Mochizuki, Tadahiko Mashino

Research output: Contribution to journalArticlepeer-review

27 Citations (Scopus)


In order to examine the utility of fullerene as a medicinal application, we evaluated the reaction between fullerene derivatives and active oxygen species in vitro. This paper describes the synthesis of various water-soluble C60 derivatives (cationic and anionic) and evaluation of their superoxide (O2-) quenching activity. Cationic C60 derivatives showed fairly high efficiency.

Original languageEnglish
Pages (from-to)127-142
Number of pages16
JournalFullerene Science and Technology
Issue number3
Publication statusPublished - 2000 Jan 1

ASJC Scopus subject areas

  • Chemical Engineering(all)


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