Synthesis of various water-soluble C60 derivatives and their superoxide-quenching activity

Kensuke Okuda, Takashi Hirota, Masaaki Hirobe, Tetsuo Nagano, Masataka Mochizuki, Tadahiko Mashino

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

In order to examine the utility of fullerene as a medicinal application, we evaluated the reaction between fullerene derivatives and active oxygen species in vitro. This paper describes the synthesis of various water-soluble C60 derivatives (cationic and anionic) and evaluation of their superoxide (O2-) quenching activity. Cationic C60 derivatives showed fairly high efficiency.

Original languageEnglish
Pages (from-to)127-142
Number of pages16
JournalFullerene Science and Technology
Volume8
Issue number3
Publication statusPublished - 2000

Fingerprint

inorganic peroxides
Superoxides
fullerenes
Fullerenes
Quenching
quenching
Derivatives
Water
synthesis
water
evaluation
Reactive Oxygen Species
oxygen
Oxygen

ASJC Scopus subject areas

  • Chemical Engineering(all)

Cite this

Synthesis of various water-soluble C60 derivatives and their superoxide-quenching activity. / Okuda, Kensuke; Hirota, Takashi; Hirobe, Masaaki; Nagano, Tetsuo; Mochizuki, Masataka; Mashino, Tadahiko.

In: Fullerene Science and Technology, Vol. 8, No. 3, 2000, p. 127-142.

Research output: Contribution to journalArticle

Okuda, K, Hirota, T, Hirobe, M, Nagano, T, Mochizuki, M & Mashino, T 2000, 'Synthesis of various water-soluble C60 derivatives and their superoxide-quenching activity', Fullerene Science and Technology, vol. 8, no. 3, pp. 127-142.
Okuda, Kensuke ; Hirota, Takashi ; Hirobe, Masaaki ; Nagano, Tetsuo ; Mochizuki, Masataka ; Mashino, Tadahiko. / Synthesis of various water-soluble C60 derivatives and their superoxide-quenching activity. In: Fullerene Science and Technology. 2000 ; Vol. 8, No. 3. pp. 127-142.
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