Synthetic studies of erythromycins. II. Enantiospecific synthesis of A C-10-C-13 segment of erythronolide a from D-ribose

Mitsuhiro Kinoshita, Masayuki Arai, Katsuhiko Tomooka, Masaya Nakata

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

(3R,4R,5R)-5-0-Benzyl-2-iodo-3,4-0-isopropylidene-4-methyl-1-heptene-3,4,5-triol 3, a C-10-C-13 synthetic segment of erythronolide A (1) was enantiospecifically synthesized in sixteen steps and 8.3% overall yield from D-ribose.

Original languageEnglish
Pages (from-to)1811-1814
Number of pages4
JournalTetrahedron Letters
Volume27
Issue number16
DOIs
Publication statusPublished - 1986

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ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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