Synthetic studies of rifamycins. VI. Preparation and elaboration of the aromatic segment for the synthesis of rifamycin W

Masaya Nakata; Mitsuhiro Kinoshita; Shigeru Ohba; Yoshihiko Saito

doi:10.1016/S0040-4039(01)80161-1

Synthetic studies of rifamycins. VI. Preparation and elaboration of the aromatic segment for the synthesis of rifamycin W

Masaya Nakata, Mitsuhiro Kinoshita, Shigeru Ohba, Yoshihiko Saito

Research output: Contribution to journal › Article › peer-review

15 Citations (Scopus)

Abstract

A convenient preparation of the aromatic segment 3 starting from 3,5-dibromo-2,6-dimethoxytoluene 5 and furan was described along with the elaboration of 3 by the aldol coupling with the aliphatic segment 2 to the synthetic precursor 4 of rifamycin W.

Original language	English
Pages (from-to)	1373-1376
Number of pages	4
Journal	Tetrahedron Letters
Volume	25
Issue number	13
DOIs	https://doi.org/10.1016/S0040-4039(01)80161-1
Publication status	Published - 1984

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/S0040-4039(01)80161-1

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title = "Synthetic studies of rifamycins. VI. Preparation and elaboration of the aromatic segment for the synthesis of rifamycin W",

abstract = "A convenient preparation of the aromatic segment 3 starting from 3,5-dibromo-2,6-dimethoxytoluene 5 and furan was described along with the elaboration of 3 by the aldol coupling with the aliphatic segment 2 to the synthetic precursor 4 of rifamycin W.",

author = "Masaya Nakata and Mitsuhiro Kinoshita and Shigeru Ohba and Yoshihiko Saito",

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AU - Nakata, Masaya

AU - Kinoshita, Mitsuhiro

AU - Ohba, Shigeru

AU - Saito, Yoshihiko

PY - 1984

Y1 - 1984

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AB - A convenient preparation of the aromatic segment 3 starting from 3,5-dibromo-2,6-dimethoxytoluene 5 and furan was described along with the elaboration of 3 by the aldol coupling with the aliphatic segment 2 to the synthetic precursor 4 of rifamycin W.

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JO - Tetrahedron Letters

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Synthetic studies of rifamycins. VI. Preparation and elaboration of the aromatic segment for the synthesis of rifamycin W

Abstract

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