Synthetic studies of rifamycins. VI. Preparation and elaboration of the aromatic segment for the synthesis of rifamycin W

Masaya Nakata, Mitsuhiro Kinoshita, Shigeru Ohba, Yoshihiko Saito

Research output: Contribution to journalArticlepeer-review

14 Citations (Scopus)

Abstract

A convenient preparation of the aromatic segment 3 starting from 3,5-dibromo-2,6-dimethoxytoluene 5 and furan was described along with the elaboration of 3 by the aldol coupling with the aliphatic segment 2 to the synthetic precursor 4 of rifamycin W.

Original languageEnglish
Pages (from-to)1373-1376
Number of pages4
JournalTetrahedron Letters
Volume25
Issue number13
DOIs
Publication statusPublished - 1984

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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