Synthetic studies of rifamycins. VI. Preparation and elaboration of the aromatic segment for the synthesis of rifamycin W

Masaya Nakata; Mitsuhiro Kinoshita; Shigeru Ohba; Yoshihiko Saito

doi:10.1016/S0040-4039(01)80161-1

Synthetic studies of rifamycins. VI. Preparation and elaboration of the aromatic segment for the synthesis of rifamycin W

Masaya Nakata, Mitsuhiro Kinoshita, Shigeru Ohba, Yoshihiko Saito

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14 Citations (Scopus)

Abstract

A convenient preparation of the aromatic segment 3 starting from 3,5-dibromo-2,6-dimethoxytoluene 5 and furan was described along with the elaboration of 3 by the aldol coupling with the aliphatic segment 2 to the synthetic precursor 4 of rifamycin W.

Original language	English
Pages (from-to)	1373-1376
Number of pages	4
Journal	Tetrahedron Letters
Volume	25
Issue number	13
DOIs	https://doi.org/10.1016/S0040-4039(01)80161-1
Publication status	Published - 1984

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ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

Cite this

Nakata, M., Kinoshita, M., Ohba, S., & Saito, Y. (1984). Synthetic studies of rifamycins. VI. Preparation and elaboration of the aromatic segment for the synthesis of rifamycin W. Tetrahedron Letters, 25(13), 1373-1376. https://doi.org/10.1016/S0040-4039(01)80161-1

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abstract = "A convenient preparation of the aromatic segment 3 starting from 3,5-dibromo-2,6-dimethoxytoluene 5 and furan was described along with the elaboration of 3 by the aldol coupling with the aliphatic segment 2 to the synthetic precursor 4 of rifamycin W.",

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10.1016/S0040-4039(01)80161-1