Synthetic studies of zoanthamine/norzoanthamine alkaloids: Advanced intermediate for the heterocyclic aminal core

Naotsuka Hikage, Hironori Furukawa, Ken ichi Takao, Susumu Kobayashi

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

An advanced intermediate for the heterocyclic aminal core of zoanthamine/norzoanthamine alkaloids was prepared in an enantio and stereoselective manner. Contiguous quaternary chiral centers were selectively constructed utilizing a stereoselective cuprate addition to the readily available (+)-Wieland-Miescher ketone.

Original languageEnglish
Pages (from-to)6237-6240
Number of pages4
JournalTetrahedron Letters
Volume39
Issue number34
DOIs
Publication statusPublished - 1998 Aug 20
Externally publishedYes

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Keywords

  • Alkaloids;animals;amino;ketones;marine metabolites

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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