Synthetic studies of zoanthamine/norzoanthamine alkaloids: Construction of the heterocyclic aminal core (CDEFG ring)

Naotsuka Hikage, Hironori Furukawa, Ken Ichi Takao, Susumu Kobayashi

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

Stereocontrolled construction of the fully functionalized heterocyclic aminal core (CDEFG ring) of the zoanthamine and norzoanthamine family was successfully accomplished from the monacyclic ketoacid which was prepared from (+)-Wieland-Miescher ketone and D-glutamic acid.

Original languageEnglish
Pages (from-to)6241-6244
Number of pages4
JournalTetrahedron Letters
Volume39
Issue number34
DOIs
Publication statusPublished - 1998 Aug 20
Externally publishedYes

Keywords

  • Alkaloids
  • Aminals
  • Amino ketones
  • Marine metabolites

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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