Synthetic studies of zoanthamine/norzoanthamine: Biogenetic-like one-step construction of the heterocyclic aminal core (CDEFG ring) from a monocyclic precursor

Naotsuka Hikage; Hironori Furukawa; Ken Ichi Takao; Kobayashi Susumu

doi:10.1248/cpb.48.1370

Synthetic studies of zoanthamine/norzoanthamine: Biogenetic-like one-step construction of the heterocyclic aminal core (CDEFG ring) from a monocyclic precursor

Naotsuka Hikage, Hironori Furukawa, Ken Ichi Takao, Kobayashi Susumu

Department of Applied Chemistry

Research output: Contribution to journal › Article › peer-review

32 Citations (Scopus)

Abstract

Biogenetic-like one-step construction of the pentacyclic aminal core of zoanthamine/norzoanthamine alkaloids was accomplished in high yield from the suitably protected monocyclic aminohydroxy diketocarboxylic acid 7 by heating in aqueous acetic acid.

Original language	English
Pages (from-to)	1370-1372
Number of pages	3
Journal	Chemical and Pharmaceutical Bulletin
Volume	48
Issue number	9
DOIs	https://doi.org/10.1248/cpb.48.1370
Publication status	Published - 2000

Keywords

Alkaloid
Aminal
Norzoanthamine
Polycycle
Tandem reaction

ASJC Scopus subject areas

Chemistry(all)
Drug Discovery

Access to Document

10.1248/cpb.48.1370

Cite this

Synthetic studies of zoanthamine/norzoanthamine : Biogenetic-like one-step construction of the heterocyclic aminal core (CDEFG ring) from a monocyclic precursor. / Hikage, Naotsuka; Furukawa, Hironori; Takao, Ken Ichi et al.

In: Chemical and Pharmaceutical Bulletin, Vol. 48, No. 9, 2000, p. 1370-1372.

Research output: Contribution to journal › Article › peer-review

@article{50d6458684b34b8894dd21151fe9b199,

title = "Synthetic studies of zoanthamine/norzoanthamine: Biogenetic-like one-step construction of the heterocyclic aminal core (CDEFG ring) from a monocyclic precursor",

abstract = "Biogenetic-like one-step construction of the pentacyclic aminal core of zoanthamine/norzoanthamine alkaloids was accomplished in high yield from the suitably protected monocyclic aminohydroxy diketocarboxylic acid 7 by heating in aqueous acetic acid.",

keywords = "Alkaloid, Aminal, Norzoanthamine, Polycycle, Tandem reaction",

author = "Naotsuka Hikage and Hironori Furukawa and Takao, {Ken Ichi} and Kobayashi Susumu",

year = "2000",

doi = "10.1248/cpb.48.1370",

language = "English",

volume = "48",

pages = "1370--1372",

journal = "Chemical and Pharmaceutical Bulletin",

issn = "0009-2363",

publisher = "Pharmaceutical Society of Japan",

number = "9",

}

TY - JOUR

T1 - Synthetic studies of zoanthamine/norzoanthamine

T2 - Biogenetic-like one-step construction of the heterocyclic aminal core (CDEFG ring) from a monocyclic precursor

AU - Hikage, Naotsuka

AU - Furukawa, Hironori

AU - Takao, Ken Ichi

AU - Susumu, Kobayashi

PY - 2000

Y1 - 2000

N2 - Biogenetic-like one-step construction of the pentacyclic aminal core of zoanthamine/norzoanthamine alkaloids was accomplished in high yield from the suitably protected monocyclic aminohydroxy diketocarboxylic acid 7 by heating in aqueous acetic acid.

AB - Biogenetic-like one-step construction of the pentacyclic aminal core of zoanthamine/norzoanthamine alkaloids was accomplished in high yield from the suitably protected monocyclic aminohydroxy diketocarboxylic acid 7 by heating in aqueous acetic acid.

KW - Alkaloid

KW - Aminal

KW - Norzoanthamine

KW - Polycycle

KW - Tandem reaction

UR - http://www.scopus.com/inward/record.url?scp=0033777106&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0033777106&partnerID=8YFLogxK

U2 - 10.1248/cpb.48.1370

DO - 10.1248/cpb.48.1370

M3 - Article

C2 - 10993242

AN - SCOPUS:0033777106

SN - 0009-2363

VL - 48

SP - 1370

EP - 1372

JO - Chemical and Pharmaceutical Bulletin

JF - Chemical and Pharmaceutical Bulletin

IS - 9

ER -

Synthetic studies of zoanthamine/norzoanthamine: Biogenetic-like one-step construction of the heterocyclic aminal core (CDEFG ring) from a monocyclic precursor

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this