Synthetic studies on altohyrtins (spongistatins)

Synthesis of the C15- C28 (CD) spiroacetal portion

Takeshi Terauchi, Taro Terauchi, Ippei Sato, Tomoharu Tsukada, Naoki Kanoh, Masaya Nakata

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

The C15-C28 portion of altohyrtins (spongistatins) was prepared in a convergent manner from methyl (S)-3-hydroxy-2-methylpropionate, D-arabitol, and diacetone-D-glucose via dithiane couplings with epoxides as the key segment coupling process. (C) 2000 Elsevier Science Ltd.

Original languageEnglish
Pages (from-to)2649-2653
Number of pages5
JournalTetrahedron Letters
Volume41
Issue number15
DOIs
Publication statusPublished - 2000 Apr 8

Fingerprint

Epoxy Compounds
Glucose
arabitol
dithiane
1,2-5,6-di-O-isopropylidene-D-glucofuranose

Keywords

  • Altohyrtins
  • Dithianes
  • Epoxides
  • Spiro compounds

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Synthetic studies on altohyrtins (spongistatins) : Synthesis of the C15- C28 (CD) spiroacetal portion. / Terauchi, Takeshi; Terauchi, Taro; Sato, Ippei; Tsukada, Tomoharu; Kanoh, Naoki; Nakata, Masaya.

In: Tetrahedron Letters, Vol. 41, No. 15, 08.04.2000, p. 2649-2653.

Research output: Contribution to journalArticle

Terauchi, T, Terauchi, T, Sato, I, Tsukada, T, Kanoh, N & Nakata, M 2000, 'Synthetic studies on altohyrtins (spongistatins): Synthesis of the C15- C28 (CD) spiroacetal portion', Tetrahedron Letters, vol. 41, no. 15, pp. 2649-2653. https://doi.org/10.1016/S0040-4039(00)00237-9
Terauchi, Takeshi ; Terauchi, Taro ; Sato, Ippei ; Tsukada, Tomoharu ; Kanoh, Naoki ; Nakata, Masaya. / Synthetic studies on altohyrtins (spongistatins) : Synthesis of the C15- C28 (CD) spiroacetal portion. In: Tetrahedron Letters. 2000 ; Vol. 41, No. 15. pp. 2649-2653.
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