@article{1a2075e37832485ba7fbde0ee188ac04,
title = "Synthetic Studies on Aplyronine A, a Potent Antitumor Substance of Marine Origin: Stereocontrolled Synthesis of the C21-C34 Segment",
abstract = "The C21-C34 segment 2 of aplyronine A (1), a potent antitumor substance of marine origin, was synthesized enantioselectively in 25 steps (17% overall yield) from imide 11.",
author = "Hideo Kigoshi and Makoto Ojika and Kiyotake Suenaga and Tsuyoshi Mutou and Junko Hirano and Akira Sakakura and Takeshi Ogawa and Masanori Nisiwaki and Kiyoyuki Yamada",
note = "Funding Information: Aeknowledgtnent. This work was supportedin part by Grants-in-Aid for Scientific Research( Nos. CkUXOO9a nd 03640472)a nd for Scientific Researcho n Prlorlty Area (Asymmetric Synthesiso f Chiral Molecules) from the Ministry of Education, Science,a nd Culture, Japan, the Fujisawa Foundation, the Shorai Foundation for Science and Technology, the Naito Foundation, the Ciba-Geigy Foundation (Japan) for the Promotion of Science, the Kowa Life Science Foundation, and the Asahi Glass Foundation. We thank Mr. Takaya Tsuboi for technical assistance.",
year = "1994",
month = feb,
day = "21",
doi = "10.1016/0040-4039(94)88035-2",
language = "English",
volume = "35",
pages = "1247--1250",
journal = "Tetrahedron Letters",
issn = "0040-4039",
publisher = "Elsevier Limited",
number = "8",
}
