Synthetic studies on biscembranoids: Asymmetric total synthesis of methyl sarcoate

Takahiro Ichige, Satoshi Kamimura, Kazuya Mayumi, Yasuyuki Sakamoto, Shingo Terashita, Eriko Ohteki, Naoki Kanoh, Masaya Nakata

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)

Abstract

The asymmetric total synthesis of a marine natural product, methyl sarcoate, has been achieved featuring the asymmetric Michael addition, the dithiane coupling, the Kosugi-Migita-Stille coupling, and the ring-closing metathesis.

Original languageEnglish
Pages (from-to)1263-1267
Number of pages5
JournalTetrahedron Letters
Volume46
Issue number8
DOIs
Publication statusPublished - 2005 Feb 21
Externally publishedYes

Keywords

  • Biscembranoid
  • Dithiane
  • Kosugi-Migita-Stille coupling
  • Methyl sarcoate
  • Ring-closing metathesis

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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