The cyclic peptide portion of chlorofusin was synthesized by condensation of the five segments, d-Ada-OTMSE, Boc-l.-Orn(Cbz), Boc-l-Thr-l-Ala, l-Asn(Tr)-d-Asn(Tr)-d-Leu-OTMSE, and Boc-l-Thr-d-Leu, followed by cyclization at the amide bond between d-Ada and l-Orn.
|Number of pages||17|
|Publication status||Published - 2007 Apr 13|
ASJC Scopus subject areas
- Analytical Chemistry
- Organic Chemistry