Synthetic studies on chlorofusin: Synthesis of the cyclic peptide portion

Tomonori Mori, Marie Miyagi, Kengo Suzuki, Mitsuhito Shibasaki, Yoko Saikawa, Masaya Nakata

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9 Citations (Scopus)

Abstract

The cyclic peptide portion of chlorofusin was synthesized by condensation of the five segments, d-Ada-OTMSE, Boc-l.-Orn(Cbz), Boc-l-Thr-l-Ala, l-Asn(Tr)-d-Asn(Tr)-d-Leu-OTMSE, and Boc-l-Thr-d-Leu, followed by cyclization at the amide bond between d-Ada and l-Orn.

Original languageEnglish
Pages (from-to)275-291
Number of pages17
JournalHeterocycles
Volume72
Publication statusPublished - 2007 Apr 13

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ASJC Scopus subject areas

  • Analytical Chemistry
  • Pharmacology
  • Organic Chemistry

Cite this

Mori, T., Miyagi, M., Suzuki, K., Shibasaki, M., Saikawa, Y., & Nakata, M. (2007). Synthetic studies on chlorofusin: Synthesis of the cyclic peptide portion. Heterocycles, 72, 275-291.