Synthetic studies on chlorofusin: Synthesis of the cyclic peptide portion

Tomonori Mori; Marie Miyagi; Kengo Suzuki; Mitsuhito Shibasaki; Yoko Saikawa; Masaya Nakata

Synthetic studies on chlorofusin: Synthesis of the cyclic peptide portion

Tomonori Mori, Marie Miyagi, Kengo Suzuki, Mitsuhito Shibasaki, Yoko Saikawa, Masaya Nakata

Department of Applied Chemistry

Research output: Contribution to journal › Article

9 Citations (Scopus)

Abstract

The cyclic peptide portion of chlorofusin was synthesized by condensation of the five segments, d-Ada-OTMSE, Boc-l.-Orn(Cbz), Boc-l-Thr-l-Ala, l-Asn(Tr)-d-Asn(Tr)-d-Leu-OTMSE, and Boc-l-Thr-d-Leu, followed by cyclization at the amide bond between d-Ada and l-Orn.

Original language	English
Pages (from-to)	275-291
Number of pages	17
Journal	Heterocycles
Volume	72
Publication status	Published - 2007 Apr 13

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ASJC Scopus subject areas

Analytical Chemistry
Pharmacology
Organic Chemistry

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Mori, T., Miyagi, M., Suzuki, K., Shibasaki, M., Saikawa, Y., & Nakata, M. (2007). Synthetic studies on chlorofusin: Synthesis of the cyclic peptide portion. Heterocycles, 72, 275-291.

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T2 - Synthesis of the cyclic peptide portion

AU - Mori, Tomonori

AU - Miyagi, Marie

AU - Suzuki, Kengo

AU - Shibasaki, Mitsuhito

AU - Saikawa, Yoko

AU - Nakata, Masaya

PY - 2007/4/13

Y1 - 2007/4/13

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AB - The cyclic peptide portion of chlorofusin was synthesized by condensation of the five segments, d-Ada-OTMSE, Boc-l.-Orn(Cbz), Boc-l-Thr-l-Ala, l-Asn(Tr)-d-Asn(Tr)-d-Leu-OTMSE, and Boc-l-Thr-d-Leu, followed by cyclization at the amide bond between d-Ada and l-Orn.

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JO - Heterocycles

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ER -

Synthetic studies on chlorofusin: Synthesis of the cyclic peptide portion

Abstract

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ASJC Scopus subject areas

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