Synthetic studies on concanamycin A: Synthesis of the C5~C13 and C20~C28 segments

Takaaki Jyojima; Masataka Katohno; Naoki Miyamoto; Masaya Nakata; Shuichi Matsumura; Kazunobu Toshima

doi:10.1016/S0040-4039(98)01233-7

Synthetic studies on concanamycin A: Synthesis of the C5~C13 and C20~C28 segments

Takaaki Jyojima, Masataka Katohno, Naoki Miyamoto, Masaya Nakata, Shuichi Matsumura, Kazunobu Toshima

Department of Applied Chemistry

Research output: Contribution to journal › Article › peer-review

22 Citations (Scopus)

Abstract

The enantioselective synthesis of the C5~C13 (2) and C20~C28 (3) segments, which are promising synthetic intermediates toward the total synthesis of the 18-membered macrolide antibiotic, concanamycin A (1), were described.

Original language	English
Pages (from-to)	6003-6006
Number of pages	4
Journal	Tetrahedron Letters
Volume	39
Issue number	33
DOIs	https://doi.org/10.1016/S0040-4039(98)01233-7
Publication status	Published - 1998 Aug 13

Keywords

Concanamycin A
Macrolides
Segment synthesis
Vacuolar H -ATPase inhibitor

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/S0040-4039(98)01233-7

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title = "Synthetic studies on concanamycin A: Synthesis of the C5~C13 and C20~C28 segments",

abstract = "The enantioselective synthesis of the C5~C13 (2) and C20~C28 (3) segments, which are promising synthetic intermediates toward the total synthesis of the 18-membered macrolide antibiotic, concanamycin A (1), were described.",

keywords = "Concanamycin A, Macrolides, Segment synthesis, Vacuolar H -ATPase inhibitor",

author = "Takaaki Jyojima and Masataka Katohno and Naoki Miyamoto and Masaya Nakata and Shuichi Matsumura and Kazunobu Toshima",

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T2 - Synthesis of the C5~C13 and C20~C28 segments

AU - Jyojima, Takaaki

AU - Katohno, Masataka

AU - Miyamoto, Naoki

AU - Nakata, Masaya

AU - Matsumura, Shuichi

AU - Toshima, Kazunobu

PY - 1998/8/13

Y1 - 1998/8/13

N2 - The enantioselective synthesis of the C5~C13 (2) and C20~C28 (3) segments, which are promising synthetic intermediates toward the total synthesis of the 18-membered macrolide antibiotic, concanamycin A (1), were described.

AB - The enantioselective synthesis of the C5~C13 (2) and C20~C28 (3) segments, which are promising synthetic intermediates toward the total synthesis of the 18-membered macrolide antibiotic, concanamycin A (1), were described.

KW - Concanamycin A

KW - Macrolides

KW - Segment synthesis

KW - Vacuolar H -ATPase inhibitor

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Synthetic studies on concanamycin A: Synthesis of the C5~C13 and C20~C28 segments

Abstract

Keywords

ASJC Scopus subject areas

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