Synthetic studies on concanamycin A: Synthesis of the C5~C13 and C20~C28 segments

Takaaki Jyojima, Masataka Katohno, Naoki Miyamoto, Masaya Nakata, Shuichi Matsumura, Kazunobu Toshima

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20 Citations (Scopus)

Abstract

The enantioselective synthesis of the C5~C13 (2) and C20~C28 (3) segments, which are promising synthetic intermediates toward the total synthesis of the 18-membered macrolide antibiotic, concanamycin A (1), were described.

Original languageEnglish
Pages (from-to)6003-6006
Number of pages4
JournalTetrahedron Letters
Volume39
Issue number33
DOIs
Publication statusPublished - 1998 Aug 13

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Keywords

  • Concanamycin A
  • Macrolides
  • Segment synthesis
  • Vacuolar H -ATPase inhibitor

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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