Synthetic studies on concanamycin A: Total synthesis of concanolide A (concanamycin F)

Takaaki Jyojima, Naoki Miyamoto, Masataka Katohno, Masaya Nakata, Shuichi Matsumura, Kazunobu Toshima

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

Enantioselective first total synthesis of concanolide A (concanamycin F), which is one of a new class of macrolide antibiotics, concanamycins, has been achieved by a highly effective and convergent route.

Original languageEnglish
Pages (from-to)6007-6010
Number of pages4
JournalTetrahedron Letters
Volume39
Issue number33
DOIs
Publication statusPublished - 1998 Aug 13

Fingerprint

Macrolides
Anti-Bacterial Agents
concanamycin F
concanamycin A

Keywords

  • Aldol reaction
  • Concanamycin F
  • Concanolide A
  • Lactonization, Stille reaction
  • Vacular H -ATPase inhibitor

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Synthetic studies on concanamycin A : Total synthesis of concanolide A (concanamycin F). / Jyojima, Takaaki; Miyamoto, Naoki; Katohno, Masataka; Nakata, Masaya; Matsumura, Shuichi; Toshima, Kazunobu.

In: Tetrahedron Letters, Vol. 39, No. 33, 13.08.1998, p. 6007-6010.

Research output: Contribution to journalArticle

Jyojima, Takaaki ; Miyamoto, Naoki ; Katohno, Masataka ; Nakata, Masaya ; Matsumura, Shuichi ; Toshima, Kazunobu. / Synthetic studies on concanamycin A : Total synthesis of concanolide A (concanamycin F). In: Tetrahedron Letters. 1998 ; Vol. 39, No. 33. pp. 6007-6010.
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