Synthetic studies on concanamycin A: Total synthesis of concanolide A (concanamycin F)

Takaaki Jyojima; Naoki Miyamoto; Masataka Katohno; Masaya Nakata; Shuichi Matsumura; Kazunobu Toshima

doi:10.1016/S0040-4039(98)01234-9

Synthetic studies on concanamycin A: Total synthesis of concanolide A (concanamycin F)

Takaaki Jyojima, Naoki Miyamoto, Masataka Katohno, Masaya Nakata, Shuichi Matsumura, Kazunobu Toshima

Department of Applied Chemistry

Research output: Contribution to journal › Article › peer-review

27 Citations (Scopus)

Abstract

Enantioselective first total synthesis of concanolide A (concanamycin F), which is one of a new class of macrolide antibiotics, concanamycins, has been achieved by a highly effective and convergent route.

Original language	English
Pages (from-to)	6007-6010
Number of pages	4
Journal	Tetrahedron Letters
Volume	39
Issue number	33
DOIs	https://doi.org/10.1016/S0040-4039(98)01234-9
Publication status	Published - 1998 Aug 13

Keywords

Aldol reaction
Concanamycin F
Concanolide A
Lactonization, Stille reaction
Vacular H -ATPase inhibitor

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/S0040-4039(98)01234-9

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abstract = "Enantioselective first total synthesis of concanolide A (concanamycin F), which is one of a new class of macrolide antibiotics, concanamycins, has been achieved by a highly effective and convergent route.",

keywords = "Aldol reaction, Concanamycin F, Concanolide A, Lactonization, Stille reaction, Vacular H -ATPase inhibitor",

author = "Takaaki Jyojima and Naoki Miyamoto and Masataka Katohno and Masaya Nakata and Shuichi Matsumura and Kazunobu Toshima",

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T2 - Total synthesis of concanolide A (concanamycin F)

AU - Jyojima, Takaaki

AU - Miyamoto, Naoki

AU - Katohno, Masataka

AU - Nakata, Masaya

AU - Matsumura, Shuichi

AU - Toshima, Kazunobu

PY - 1998/8/13

Y1 - 1998/8/13

N2 - Enantioselective first total synthesis of concanolide A (concanamycin F), which is one of a new class of macrolide antibiotics, concanamycins, has been achieved by a highly effective and convergent route.

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KW - Aldol reaction

KW - Concanamycin F

KW - Concanolide A

KW - Lactonization, Stille reaction

KW - Vacular H -ATPase inhibitor

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ER -

Synthetic studies on concanamycin A: Total synthesis of concanolide A (concanamycin F)

Abstract

Keywords

ASJC Scopus subject areas

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