Synthetic studies on glycosphingolipids from protostomia phyla: Synthesis of glycosphingolipid from the marine sponge Spheciospongia vesparia and its analogue

Noriyasu Hada; Akira Miyamura; Isao Ohtsuka; Fumiyuki Kiuchi

doi:10.3987/COM-13-S(S)23

Synthetic studies on glycosphingolipids from protostomia phyla: Synthesis of glycosphingolipid from the marine sponge Spheciospongia vesparia and its analogue

Noriyasu Hada, Akira Miyamura, Isao Ohtsuka, Fumiyuki Kiuchi

School of Pharmacy

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

Stereocontrolled syntheses of a neutral glycosphingolipid found from a marine sponge Spheciospongia vesparia and its analogue have been accomplished. Disaccharide glycosphingolipids, β-D-Arap-(1→6)-β-D-Glcp-(1↔1)-Cer (1) and α-D-Arap-(1→6)-β-D-Glcp-(1↔1)-Cer (2), were synthesized from suitable monosaccharide donors and an acceptor by stepwise synthesis.

Original language	English
Pages (from-to)	689-704
Number of pages	16
Journal	Heterocycles
Volume	88
Issue number	1
DOIs	https://doi.org/10.3987/COM-13-S(S)23
Publication status	Published - 2014

ASJC Scopus subject areas

Analytical Chemistry
Pharmacology
Organic Chemistry

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abstract = "Stereocontrolled syntheses of a neutral glycosphingolipid found from a marine sponge Spheciospongia vesparia and its analogue have been accomplished. Disaccharide glycosphingolipids, β-D-Arap-(1→6)-β-D-Glcp-(1↔1)-Cer (1) and α-D-Arap-(1→6)-β-D-Glcp-(1↔1)-Cer (2), were synthesized from suitable monosaccharide donors and an acceptor by stepwise synthesis.",

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AU - Hada, Noriyasu

AU - Miyamura, Akira

AU - Ohtsuka, Isao

AU - Kiuchi, Fumiyuki

PY - 2014

Y1 - 2014

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AB - Stereocontrolled syntheses of a neutral glycosphingolipid found from a marine sponge Spheciospongia vesparia and its analogue have been accomplished. Disaccharide glycosphingolipids, β-D-Arap-(1→6)-β-D-Glcp-(1↔1)-Cer (1) and α-D-Arap-(1→6)-β-D-Glcp-(1↔1)-Cer (2), were synthesized from suitable monosaccharide donors and an acceptor by stepwise synthesis.

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Synthetic studies on glycosphingolipids from protostomia phyla: Synthesis of glycosphingolipid from the marine sponge Spheciospongia vesparia and its analogue

Abstract

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