Synthetic studies on oligomycins. Enantiospecific synthesis of the oligomycin B spiroketal portion and establishment of the absolute stereochemistry of oligomycin B

Masaya Nakata, Takashi Ishiyama, Youichi Hirose, Hiroshi Maruoka, Kuniaki Tatsuta

Research output: Contribution to journalArticlepeer-review

12 Citations (Scopus)

Abstract

The enantiospecific synthesis of the oligomycin B degradation product 2, corresponding to the C19-C34 spiroketal portion, has been achieved by sequential coupling of the C19-C21, C22-C27, and C28-C34 subunits, establishing the absolute stereochemistry of oligomycin B.

Original languageEnglish
Pages (from-to)8439-8442
Number of pages4
JournalTetrahedron Letters
Volume34
Issue number52
DOIs
Publication statusPublished - 1993

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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