Synthetic studies on polymaxenolides: Synthesis and structure elucidation of nominal epoxyafricanane and other africane-type sesquiterpenoids

Yutaka Matsuda, Yusuke Endo, Yoko Saikawa, Masaya Nakata

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)

Abstract

A racemic total synthesis of the sesquiterpenoid unit of the hybrid marine natural product polymaxenolide has been achieved based on a three-component assembly followed by ring-closing metathesis as the key steps. However, the spectral data of our product synthesized from Δ 9(15)-africanene by epoxidation were not identical with those of the natural product named epoxyafricanane. The structure confirmation of the synthetic nominal epoxyafricanane is described.

Original languageEnglish
Pages (from-to)6258-6263
Number of pages6
JournalJournal of Organic Chemistry
Volume76
Issue number15
DOIs
Publication statusPublished - 2011 Aug 5

ASJC Scopus subject areas

  • Organic Chemistry

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