Synthetic studies on reidispongiolide A, an actin-depolymerizing marine macrolide: synthesis of C11-C22 and C23-C35 segments

Satoshi Akiyama, Eisuke Toriihara, Kazushi Suzuki, Toshiaki Teruya, Kiyotake Suenaga

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3 Citations (Scopus)

Abstract

The C11-C22 and C23-C35 segments 2 and 3 of reidispongiolide A (1), an actin-depolymerizing marine macrolide, were synthesized enantioselectively in 12 steps from (R)-glycidyl trityl ether and in 12 steps from chiral ketone 15, respectively.

Original languageEnglish
Pages (from-to)5012-5014
Number of pages3
JournalTetrahedron Letters
Volume50
Issue number35
DOIs
Publication statusPublished - 2009 Sep 2

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ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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