Synthetic study on a 26-membered macrolide, amphidinolide B: Synthesis of the C1-C13 fragment

Katsuhide Ohi; Kyoko Shima; Kozue Hamada; Yoshio Saito; Naoki Yamada; Shigeru Ohba; Shigeru Nishiyama

doi:10.1246/bcsj.71.2433

Synthetic study on a 26-membered macrolide, amphidinolide B: Synthesis of the C₁-C₁₃ fragment

Katsuhide Ohi, Kyoko Shima, Kozue Hamada, Yoshio Saito, Naoki Yamada, Shigeru Ohba, Shigeru Nishiyama

Department of Humanities and Social Sciences

Research output: Contribution to journal › Article

27 Citations (Scopus)

Abstract

The C₁-C₁₃ fragment of amphidinolide B (1) was synthesized from D- erythrose (3). The Evans alkylation reaction protocol allowed the introduction of the stereogenic center at the C₁₁ position, which was unambiguously confirmed by a single X-ray crystallographic analysis.

Original language	English
Pages (from-to)	2433-2440
Number of pages	8
Journal	Bulletin of the Chemical Society of Japan
Volume	71
Issue number	10
DOIs	https://doi.org/10.1246/bcsj.71.2433
Publication status	Published - 1998 Oct 1

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ASJC Scopus subject areas

Chemistry(all)

Cite this

Ohi, K., Shima, K., Hamada, K., Saito, Y., Yamada, N., Ohba, S., & Nishiyama, S. (1998). Synthetic study on a 26-membered macrolide, amphidinolide B: Synthesis of the C₁-C₁₃ fragment. Bulletin of the Chemical Society of Japan, 71(10), 2433-2440. https://doi.org/10.1246/bcsj.71.2433

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Access to Document

10.1246/bcsj.71.2433