Synthetic study on a 26-membered macrolide, amphidinolide B: Synthesis of the C1-C13 fragment

Katsuhide Ohi, Kyoko Shima, Kozue Hamada, Yoshio Saito, Naoki Yamada, Shigeru Ohba, Shigeru Nishiyama

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The C1-C13 fragment of amphidinolide B (1) was synthesized from D- erythrose (3). The Evans alkylation reaction protocol allowed the introduction of the stereogenic center at the C11 position, which was unambiguously confirmed by a single X-ray crystallographic analysis.

Original languageEnglish
Pages (from-to)2433-2440
Number of pages8
JournalBulletin of the Chemical Society of Japan
Issue number10
Publication statusPublished - 1998 Oct 1


ASJC Scopus subject areas

  • Chemistry(all)

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