Tailored bioceramics of Calcium phosphates for regenerative medicine

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14 Citations (Scopus)

Abstract

Calcium phosphate bioceramics, especially those in hydroxyapatite (HA) and β-tricalcium phosphate (β-TCP), are leading candidates for scaffolds used in regenerative medicine for bone tissue. The precise control of chemical composition, pore structure, and crystal faces is important for both the tissue regeneration and bioresorption of the materials. The excellent characteristics of HA and β-TCP for cell activity could be shown by using transparent ceramics of HA and β-TCP. Both calcium phosphates prepared through hydrothermal processing composed of rod-shaped particles were compared to conventional materials prepared by sintering methods, and their superior properties for bone regeneration were demonstrated. The in vivo behavior of HA and β-TCP is discussed from the viewpoint of chemical dissolubility.

Original languageEnglish
Pages (from-to)775-783
Number of pages9
JournalNippon Seramikkusu Kyokai Gakujutsu Ronbunshi/Journal of the Ceramic Society of Japan
Volume118
Issue number1381
Publication statusPublished - 2010 Sep
Externally publishedYes

Fingerprint

Calcium Phosphates
Bioceramics
calcium phosphates
Calcium phosphate
Durapatite
regeneration
Hydroxyapatite
medicine
bones
sintering
phosphates
Bone
chemical composition
rods
ceramics
porosity
Tissue regeneration
Pore structure
cells
Scaffolds

Keywords

  • β-TCP
  • Bioceramics
  • Calcium phosphate
  • Hydrothermal
  • Hydroxyapatite
  • Microstructure
  • Regenerative medicine

ASJC Scopus subject areas

  • Ceramics and Composites
  • Materials Chemistry
  • Chemistry(all)
  • Condensed Matter Physics

Cite this

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AB - Calcium phosphate bioceramics, especially those in hydroxyapatite (HA) and β-tricalcium phosphate (β-TCP), are leading candidates for scaffolds used in regenerative medicine for bone tissue. The precise control of chemical composition, pore structure, and crystal faces is important for both the tissue regeneration and bioresorption of the materials. The excellent characteristics of HA and β-TCP for cell activity could be shown by using transparent ceramics of HA and β-TCP. Both calcium phosphates prepared through hydrothermal processing composed of rod-shaped particles were compared to conventional materials prepared by sintering methods, and their superior properties for bone regeneration were demonstrated. The in vivo behavior of HA and β-TCP is discussed from the viewpoint of chemical dissolubility.

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