Target-selective photo-degradation of HIV-1 protease by a fullerene-sugar hybrid

Shuho Tanimoto; Satoshi Sakai; Shuichi Matsumura; Daisuke Takahashi; Kazunobu Toshima

doi:10.1039/b811726h

Target-selective photo-degradation of HIV-1 protease by a fullerene-sugar hybrid

Shuho Tanimoto, Satoshi Sakai, Shuichi Matsumura, Daisuke Takahashi, Kazunobu Toshima

Department of Applied Chemistry

Research output: Contribution to journal › Article › peer-review

57 Citations (Scopus)

Abstract

A designed fullerene-sugar hybrid effectively and selectively degraded the target protein, HIV-1 protease, which has high affinity for the fullerene moiety; degradation was achieved using long-wavelength UV or visible photo-irradiation, in the absence of any additives and under neutral conditions.

Original language	English
Pages (from-to)	5767-5769
Number of pages	3
Journal	Chemical Communications
Issue number	44
DOIs	https://doi.org/10.1039/b811726h
Publication status	Published - 2008

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
Chemistry(all)
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1039/b811726h

Cite this

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abstract = "A designed fullerene-sugar hybrid effectively and selectively degraded the target protein, HIV-1 protease, which has high affinity for the fullerene moiety; degradation was achieved using long-wavelength UV or visible photo-irradiation, in the absence of any additives and under neutral conditions.",

author = "Shuho Tanimoto and Satoshi Sakai and Shuichi Matsumura and Daisuke Takahashi and Kazunobu Toshima",

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AU - Tanimoto, Shuho

AU - Sakai, Satoshi

AU - Matsumura, Shuichi

AU - Takahashi, Daisuke

AU - Toshima, Kazunobu

PY - 2008

Y1 - 2008

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AB - A designed fullerene-sugar hybrid effectively and selectively degraded the target protein, HIV-1 protease, which has high affinity for the fullerene moiety; degradation was achieved using long-wavelength UV or visible photo-irradiation, in the absence of any additives and under neutral conditions.

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Target-selective photo-degradation of HIV-1 protease by a fullerene-sugar hybrid

Abstract

ASJC Scopus subject areas

UN SDGs

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