Abstract
Objective: To develop an efficient way to evaluate tear dynamics clinically. Participants: Three hundred fifty-two patients with dry eye, 64 of whom had Sjogren syndrome, and 55 normal subjects. Design: Because various forces that affect tear drainage are reflected in the values of the Schirmer test with anesthesia and the tear clearance rate, we introduced a new measure of tear dynamics, the tear function index, which is the value obtained from dividing the value of the Schirmer test with anesthesia by the tear clearance rate. Results: The tear function index was more specific (91.8%) and sensitive (78.9%) in diagnosing dry eye associated with Sjogren syndrome than was the Schirmer or tear clearance rate test alone. Tear function indexes below 96 were consistent with dry eye and those below 34 were seen primarily in patients with Sjogren syndrome. Conclusions: The tear function index offers a new method to evaluate tear production with the Schirmer test, introduces an extended way to measure tear flow combining with tear drainage, and gives a practical measure to diagnose dry eye.
| Original language | English |
|---|---|
| Pages (from-to) | 84-88 |
| Number of pages | 5 |
| Journal | Archives of Ophthalmology |
| Volume | 113 |
| Issue number | 1 |
| Publication status | Published - 1995 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Ophthalmology
Cite this
Tear function index : A new measure of dry eye. / Xu, K. P.; Yagi, Y.; Toda, I.; Tsubota, Kazuo.
In: Archives of Ophthalmology, Vol. 113, No. 1, 1995, p. 84-88.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Tear function index
T2 - A new measure of dry eye
AU - Xu, K. P.
AU - Yagi, Y.
AU - Toda, I.
AU - Tsubota, Kazuo
PY - 1995
Y1 - 1995
N2 - Objective: To develop an efficient way to evaluate tear dynamics clinically. Participants: Three hundred fifty-two patients with dry eye, 64 of whom had Sjogren syndrome, and 55 normal subjects. Design: Because various forces that affect tear drainage are reflected in the values of the Schirmer test with anesthesia and the tear clearance rate, we introduced a new measure of tear dynamics, the tear function index, which is the value obtained from dividing the value of the Schirmer test with anesthesia by the tear clearance rate. Results: The tear function index was more specific (91.8%) and sensitive (78.9%) in diagnosing dry eye associated with Sjogren syndrome than was the Schirmer or tear clearance rate test alone. Tear function indexes below 96 were consistent with dry eye and those below 34 were seen primarily in patients with Sjogren syndrome. Conclusions: The tear function index offers a new method to evaluate tear production with the Schirmer test, introduces an extended way to measure tear flow combining with tear drainage, and gives a practical measure to diagnose dry eye.
AB - Objective: To develop an efficient way to evaluate tear dynamics clinically. Participants: Three hundred fifty-two patients with dry eye, 64 of whom had Sjogren syndrome, and 55 normal subjects. Design: Because various forces that affect tear drainage are reflected in the values of the Schirmer test with anesthesia and the tear clearance rate, we introduced a new measure of tear dynamics, the tear function index, which is the value obtained from dividing the value of the Schirmer test with anesthesia by the tear clearance rate. Results: The tear function index was more specific (91.8%) and sensitive (78.9%) in diagnosing dry eye associated with Sjogren syndrome than was the Schirmer or tear clearance rate test alone. Tear function indexes below 96 were consistent with dry eye and those below 34 were seen primarily in patients with Sjogren syndrome. Conclusions: The tear function index offers a new method to evaluate tear production with the Schirmer test, introduces an extended way to measure tear flow combining with tear drainage, and gives a practical measure to diagnose dry eye.
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M3 - Article
C2 - 7826298
AN - SCOPUS:0028878545
VL - 113
SP - 84
EP - 88
JO - JAMA Ophthalmology
JF - JAMA Ophthalmology
SN - 2168-6165
IS - 1
ER -