Temperature mapping considerations in the breast with line scan echo planar spectroscopic imaging

Nathan McDannold, Agnieszka Szot Barnes, Frank J. Rybicki, Koichi Oshio, Nan Kuei Chen, Kullervo Hynynen, Robert V. Mulkern

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19 Citations (Scopus)

Abstract

A line-scan echo planar spectroscopic imaging (LSEPSI) sequence was used to serially acquire spectra from 4096 voxels every 6.4 s throughout the breasts of nine female subjects in vivo. Data from the serial acquisitions were analyzed to determine the potential of the technique to characterize temperature changes using either the water frequency alone or the water-methylene frequency difference. Fluctuations of the apparent temperature change under these conditions of no heating were smallest using the water-methylene frequency difference, most probably due to a substantial reduction of motion effects both within and without the imaged plane. The approach offers considerable advantages over other methods for temperature change monitoring in the breast with magnetic resonance but suffers from some limitations, including the unavailability of lipid and water resonances in some voxels as well as a surprisingly large distribution of water-methylene frequency differences, which may preclude absolute temperature measurement.

Original languageEnglish
Pages (from-to)1117-1123
Number of pages7
JournalMagnetic Resonance in Medicine
Volume58
Issue number6
DOIs
Publication statusPublished - 2007 Dec 1

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Keywords

  • Breast
  • Magnetic resonance imaging
  • Thermal therapies
  • Thermometry

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

McDannold, N., Barnes, A. S., Rybicki, F. J., Oshio, K., Chen, N. K., Hynynen, K., & Mulkern, R. V. (2007). Temperature mapping considerations in the breast with line scan echo planar spectroscopic imaging. Magnetic Resonance in Medicine, 58(6), 1117-1123. https://doi.org/10.1002/mrm.21322