We measured the localized transient temperature of Ho:YAG laser induced bubble in water by infrared radiation measurement with a infrared optical fiber to study heat effect/damage of this bubble for vascular therapeutic applications. Although there have been many reports regarding to the temperature in the Ho:YAG laser induced bubble by both theoretical and experimental approaches, we can not find well-time-response reliable temperature in the laser induced bubble. We constructed the remote temperature measurement system to obtain the temperature of the laser induced bubble with the infrared optical fiber (Optran MIR, CeramOptec) made of AgCl/AgBr with 1mm in core diameter. The flash lamp excited Ho: YAG laser (IH102, NIIC,λ=2.1μm) beam was delivered through a silica optical fiber (core diameter: 600μm) and was irradiated from the fiber tip in water. The tip position of the infrared optical fiber against the silica glass fiber was changed to measure local bubble temperature. The sidewall of the infrared optical fiber tip was covered by a black rubber tube to prevent the collection of the Ho:YAG laser into the infrared fiber. The infrared radiation delivered through the infrared optical fiber was measured by the HgCdTe infrared detector (KMPC12-2-J1, Kolmar Technologies, rise time:500ns). This fiber optic radiation detection system was calibrated before the bubble temperature measurement. Since the bubble boundary location and its shape were changed with time, we corrected influences of these factors. We finally obtained the peak temperature of 61.7±2.8°C at the top surface in the laser induced bubble with 800mJ/pulse. This temperature was 10 degree lower than that of reported. The temperature at the top of the bubble was approximately 9.8 degree higher than that at the bubble side. Obtained temperature distribution with time may be available to study bubble dynamics necessary for our vascular applications.