Abstract
We have developed a new method for HPLC which uses packing materials modified with a temperature-responsive polymer, poly(N-isopropylacrylamide). The surface properties and functions of the stationary phases are controlled by the external temperature. In the proposed chromatographic system, the elution of target substances is controlled by only a small change in the column temperatures.
Original language | English |
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Pages (from-to) | 435-440 |
Number of pages | 6 |
Journal | TrAC - Trends in Analytical Chemistry |
Volume | 17 |
Issue number | 7 |
DOIs | |
Publication status | Published - 1998 Aug |
Keywords
- Poly(N- isopropylacrylamide)
- Stationary phases
- Temperature-responsive chromatography
- Thermosensitive
ASJC Scopus subject areas
- Analytical Chemistry
- Spectroscopy