Temperature-responsive chromatography

Hideko Kanazawa, Yoshikazu Matsushima, Teruo Okano

Research output: Contribution to journalArticlepeer-review

32 Citations (Scopus)


We have developed a new method for HPLC which uses packing materials modified with a temperature-responsive polymer, poly(N-isopropylacrylamide). The surface properties and functions of the stationary phases are controlled by the external temperature. In the proposed chromatographic system, the elution of target substances is controlled by only a small change in the column temperatures.

Original languageEnglish
Pages (from-to)435-440
Number of pages6
JournalTrAC - Trends in Analytical Chemistry
Issue number7
Publication statusPublished - 1998 Aug


  • Poly(N- isopropylacrylamide)
  • Stationary phases
  • Temperature-responsive chromatography
  • Thermosensitive

ASJC Scopus subject areas

  • Analytical Chemistry
  • Spectroscopy


Dive into the research topics of 'Temperature-responsive chromatography'. Together they form a unique fingerprint.

Cite this