Temperature-responsive chromatography

Y. Matsushma, Hideko Kanazawa, T. Okano

Research output: Contribution to journalArticle

Abstract

We have developed a new method for HPLC which uses packing materials modified with a temperature-responsive polymer, poly(N-isopropylacrylamide). The surface properties and functions of the stationary phases are controlled by the external temperature. In the proposed chromatographic system, the elution of target substances is controlled by only a small change in the column temperatures. Copyright (C) 1998 Elsevier Science B.V.

Original languageEnglish
Pages (from-to)435-440
Number of pages6
JournalEuropean Journal of Pharmacology
Volume367
Issue number2-3
Publication statusPublished - 1999

Fingerprint

Chromatography
Temperature
Surface Properties
Polymers
High Pressure Liquid Chromatography
poly-N-isopropylacrylamide

Keywords

  • Poly(N-isopropylacrylamide)
  • Stationary phases, thermosensitive
  • Temperature-responsive chromatography

ASJC Scopus subject areas

  • Cellular and Molecular Neuroscience
  • Pharmacology

Cite this

Matsushma, Y., Kanazawa, H., & Okano, T. (1999). Temperature-responsive chromatography. European Journal of Pharmacology, 367(2-3), 435-440.

Temperature-responsive chromatography. / Matsushma, Y.; Kanazawa, Hideko; Okano, T.

In: European Journal of Pharmacology, Vol. 367, No. 2-3, 1999, p. 435-440.

Research output: Contribution to journalArticle

Matsushma, Y, Kanazawa, H & Okano, T 1999, 'Temperature-responsive chromatography', European Journal of Pharmacology, vol. 367, no. 2-3, pp. 435-440.
Matsushma, Y. ; Kanazawa, Hideko ; Okano, T. / Temperature-responsive chromatography. In: European Journal of Pharmacology. 1999 ; Vol. 367, No. 2-3. pp. 435-440.
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