Ten families of lattice corneal dystrophy: Two different types

Ten families of lattice corneal dystrophy were reported. These families were divided into two different groups. In seven families, the corneas of affected patients revealed typical numerous delicate lattice lines and diffuse central opacities. The patients had suffered from the attacks of corneal erosion. The mode of inheritance was autosomal dominant. Five of these families were from a small town named Kurose in Hiroshima Prefacture in southern part of Honshu island. In three families, the lattice lines were much thicker and central opacities were unremarkable. There was no episode of attack of corneal erosion in all of the patients. This corneal condition resembles to the lattice dystrophy type 2 (Meretoja), but it was inherited in autosomal recessive fashion and there was no evidence of systemic amyloidosis.