Text-Displaying Colorimetric Paper-Based Analytical Device

Kentaro Yamada, Koji Suzuki, Daniel Citterio

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

This paper describes a paper-based analytical device allowing the direct semiquantitative interpretation of the result of a chemical assay in the form of "text". The combined use of a classical colorimetric indicator system and an additional inert colorant enables a versatile text-displaying detection mechanism on a paper device. For proof-of-concept, urinary protein has been selected as a model analytical target. The whole text-displaying paper device has been developed based on printing techniques including wax printing, inkjet printing, and 3D printing. The results of user tests performed with protein (human serum albumin) samples in aqueous standard solutions and human urine demonstrated that the accuracy was comparable for the elaborated paper device (74.7% for standard samples and 66.7% for urine) and a conventional colorimetric urine dipstick (67.2% for standard samples and 65.3% for urine). Storage stability as long as at least 117 days has been confirmed based on software-assisted quantitative color analysis. The developed text-displaying approach is proposed as an alternative simple detection motif for paper-based analytical devices.

Original languageEnglish
Pages (from-to)1247-1254
Number of pages8
JournalACS Sensors
Volume2
Issue number8
DOIs
Publication statusPublished - 2017 Aug 25

Keywords

  • colorimetry
  • paper-based analytical device
  • printing techniques
  • protein sensing
  • text-display

ASJC Scopus subject areas

  • Bioengineering
  • Fluid Flow and Transfer Processes
  • Process Chemistry and Technology
  • Instrumentation

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