Abstract
Purpose Strong acid electrolysed waler (SAHVv ) is produced b> electro!) sis from lap water SAEW is defined as when Hi pH is less than 2 7 and has been shown to have strong and rapid bactericidal effect against a wide spectrum ot bacteria and viruses IrHhis stud; . we investigated t he sai et \ot topi cal instillation of SAbW Since the side el feels of S Ah" W on living ceils lias been reported to be minimal, we considered its ophthalmic application. flELtoda SAh'W was produced by the principle oi Acitron(pH2 40 ORP -1 lOOmV, residual chloride lu-30ppm) We instilled 30ml ol SAEW to rabbit ( 1 rabbit. 2 eyes) and human e>es in 4) \l'ter5 and 15 minutes, we examined the cornt a] and conjutictival epithehumb) fîuoresceii) staining (tor rahhitand hurmuis) and rose heiigal staining (for humans only ;> Resylt£ in human subjects there was no vital Stauung of the cornea nor injection ot conjunctiva 5 and 15 minutes after the instillation which caused minimal irritation (44). No staining of the cornea nor coi juncu val injection were oli served in the rabbit eyes Conclusions: No major side ef'ects were observed in human and rabbit subjects .-Vlthoughmoredetailedreseaichsliould be performed clinical use ol' SAh'V\ in ophthalmologic infections may be possible inthefututv.
| Original language | English |
|---|---|
| Journal | Investigative Ophthalmology and Visual Science |
| Volume | 38 |
| Issue number | 4 |
| Publication status | Published - 1997 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Ophthalmology
Cite this
The application of strong acid electrolysed water in ophthalmology. / Hyaguchi, Takano; Fujita, H.; Tsubota, Kazuo.
In: Investigative Ophthalmology and Visual Science, Vol. 38, No. 4, 1997.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The application of strong acid electrolysed water in ophthalmology
AU - Hyaguchi, Takano
AU - Fujita, H.
AU - Tsubota, Kazuo
PY - 1997
Y1 - 1997
N2 - Purpose Strong acid electrolysed waler (SAHVv ) is produced b> electro!) sis from lap water SAEW is defined as when Hi pH is less than 2 7 and has been shown to have strong and rapid bactericidal effect against a wide spectrum ot bacteria and viruses IrHhis stud; . we investigated t he sai et \ot topi cal instillation of SAbW Since the side el feels of S Ah" W on living ceils lias been reported to be minimal, we considered its ophthalmic application. flELtoda SAh'W was produced by the principle oi Acitron(pH2 40 ORP -1 lOOmV, residual chloride lu-30ppm) We instilled 30ml ol SAEW to rabbit ( 1 rabbit. 2 eyes) and human e>es in 4) \l'ter5 and 15 minutes, we examined the cornt a] and conjutictival epithehumb) fîuoresceii) staining (tor rahhitand hurmuis) and rose heiigal staining (for humans only ;> Resylt£ in human subjects there was no vital Stauung of the cornea nor injection ot conjunctiva 5 and 15 minutes after the instillation which caused minimal irritation (44). No staining of the cornea nor coi juncu val injection were oli served in the rabbit eyes Conclusions: No major side ef'ects were observed in human and rabbit subjects .-Vlthoughmoredetailedreseaichsliould be performed clinical use ol' SAh'V\ in ophthalmologic infections may be possible inthefututv.
AB - Purpose Strong acid electrolysed waler (SAHVv ) is produced b> electro!) sis from lap water SAEW is defined as when Hi pH is less than 2 7 and has been shown to have strong and rapid bactericidal effect against a wide spectrum ot bacteria and viruses IrHhis stud; . we investigated t he sai et \ot topi cal instillation of SAbW Since the side el feels of S Ah" W on living ceils lias been reported to be minimal, we considered its ophthalmic application. flELtoda SAh'W was produced by the principle oi Acitron(pH2 40 ORP -1 lOOmV, residual chloride lu-30ppm) We instilled 30ml ol SAEW to rabbit ( 1 rabbit. 2 eyes) and human e>es in 4) \l'ter5 and 15 minutes, we examined the cornt a] and conjutictival epithehumb) fîuoresceii) staining (tor rahhitand hurmuis) and rose heiigal staining (for humans only ;> Resylt£ in human subjects there was no vital Stauung of the cornea nor injection ot conjunctiva 5 and 15 minutes after the instillation which caused minimal irritation (44). No staining of the cornea nor coi juncu val injection were oli served in the rabbit eyes Conclusions: No major side ef'ects were observed in human and rabbit subjects .-Vlthoughmoredetailedreseaichsliould be performed clinical use ol' SAh'V\ in ophthalmologic infections may be possible inthefututv.
UR - http://www.scopus.com/inward/record.url?scp=33749101068&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33749101068&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:33749101068
VL - 38
JO - Investigative Ophthalmology and Visual Science
JF - Investigative Ophthalmology and Visual Science
SN - 0146-0404
IS - 4
ER -