The association of home and accurately measured office blood pressure with coronary artery calcification among general Japanese men

Atsushi Satoh, Hisatomi Arima, Atsushi Hozawa, Takayoshi Ohkubo, Takashi Hisamatsu, Sayaka Kadowaki, Aya Kadota, Akira Fujiyoshi, Naoko Miyagawa, Maryam Zaid, Sayuki Torii, Tomonori Okamura, Akira Sekikawa, Katsuyuki Miura, Hirotsugu Ueshima

Research output: Contribution to journalArticle


Objective:We conducted a cross-sectional study to clarify whether home blood pressure (HBP) is more strongly associated with coronary artery calcification (CAC) than accurately measured office blood pressure (OBP) among the general population of Japanese men.Methods:We analyzed the data of 919 Japanese male participants who were randomly selected from general population (mean age 64.5 years). OBP was measured twice consecutively by a trained nurse using electrical device after 5 min of complete rest alone in a sitting position in a silent room. The participants were asked to measure HBP with an electrical device once in the morning during 7 consecutive days. CAC was assessed using computed tomography. Presence of CAC was defined as Agatston score at least 10. We calculated odds ratios for the presence of CAC per one SD higher OBP and HBP adjusted for age and other cardiovascular risk factors.Results:The mean systolic OBP (SD) and HBP (SD) were 136.8 (19.0) and 137.2 (18.5) mmHg, respectively, without statistical difference between the two (P = 0.595). OBP and HBP were highly correlated (r = 0.74 P < 0.001). CAC was found in 454 (49.4%) participants. Multivariable-adjusted odds ratios [95% confidence interval (CI)] for the presence of CAC were comparable between OBP (1.32, 95% CI: 1.12-1.56) and HBP (1.35, 95% CI: 1.14-1.60) (P heterogeneity = 0.813).Conclusion:The strength of association of accurately measured OBP with CAC was comparable with that of HBP among randomly selected male general population aged 40-79 years.

Original languageEnglish
Pages (from-to)1676-1681
Number of pages6
JournalJournal of hypertension
Issue number8
Publication statusPublished - 2019 Aug 1



  • cohort study
  • coronary artery calcification
  • epidemiology
  • home blood pressure
  • office blood pressure

ASJC Scopus subject areas

  • Internal Medicine
  • Physiology
  • Cardiology and Cardiovascular Medicine

Cite this

Satoh, A., Arima, H., Hozawa, A., Ohkubo, T., Hisamatsu, T., Kadowaki, S., Kadota, A., Fujiyoshi, A., Miyagawa, N., Zaid, M., Torii, S., Okamura, T., Sekikawa, A., Miura, K., & Ueshima, H. (2019). The association of home and accurately measured office blood pressure with coronary artery calcification among general Japanese men. Journal of hypertension, 37(8), 1676-1681.