Abstract
It is quite difficult to judge whether various ECG abnormalities in asymptomatic alcoholics reflect latent stage of alcoholic cardiomyopathy, because several deterioration observed at alcoholic withdrawal stage modify ECG findings. To assess the ECG abnormalities during withdrawal stage, we studied the consecutive changes of ECG abnormalities after abstinence in 48 asymptomatic alcoholics admitted within 48 hours of last drink. The incidence of high QRS voltage (Sv1+Rv6>36 mm, Sv1+Rv5>40 mm, and Sv2+Rv5> 45mm) were 25%, 10%, and 13%, QTc prolongation (QTc>0.43 sec), 71%, 27%, and 15% on admission, 7th, and 30th hospital day, respectively. The consecutive changes of their correlations with drinking profile, electrolyte imbalance, blood pressure, heart rate, cardiac autonomic nerve dysfunction assessed by heart rate variability were studied by linear regression analyses. Heavy daily alcohol consumption, electrolyte imbalance, cardiac autonomic nerve dysfunction were related with ECG abnormalities at early withdrawal stage. With the improvement of ECG abnormalities after abstinence, these relationship became poorer. These results suggest ECG abnormalities in alcoholics are affected by several deterioration at early withdrawal stage.
| Original language | English |
|---|---|
| Pages (from-to) | 222-226 |
| Number of pages | 5 |
| Journal | Japanese Journal of National Medical Services |
| Volume | 44 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 1990 |
| Externally published | Yes |
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Keywords
- alcoholism
- autonomic nervous disturbance
- electrocardiogram
- withdrawal state
ASJC Scopus subject areas
- Medicine(all)
Cite this
The Change of Ecg Findings After Abstinence in Alcoholics. / Takagi, Toshikazu; Onishi, Shohei; Maruyama, Katsuya; Takagi, Satoshi; Muramatsu, Taro; Kono, Hiroaki; Yokoyama, Akira.
In: Japanese Journal of National Medical Services, Vol. 44, No. 3, 1990, p. 222-226.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The Change of Ecg Findings After Abstinence in Alcoholics
AU - Takagi, Toshikazu
AU - Onishi, Shohei
AU - Maruyama, Katsuya
AU - Takagi, Satoshi
AU - Muramatsu, Taro
AU - Kono, Hiroaki
AU - Yokoyama, Akira
PY - 1990
Y1 - 1990
N2 - It is quite difficult to judge whether various ECG abnormalities in asymptomatic alcoholics reflect latent stage of alcoholic cardiomyopathy, because several deterioration observed at alcoholic withdrawal stage modify ECG findings. To assess the ECG abnormalities during withdrawal stage, we studied the consecutive changes of ECG abnormalities after abstinence in 48 asymptomatic alcoholics admitted within 48 hours of last drink. The incidence of high QRS voltage (Sv1+Rv6>36 mm, Sv1+Rv5>40 mm, and Sv2+Rv5> 45mm) were 25%, 10%, and 13%, QTc prolongation (QTc>0.43 sec), 71%, 27%, and 15% on admission, 7th, and 30th hospital day, respectively. The consecutive changes of their correlations with drinking profile, electrolyte imbalance, blood pressure, heart rate, cardiac autonomic nerve dysfunction assessed by heart rate variability were studied by linear regression analyses. Heavy daily alcohol consumption, electrolyte imbalance, cardiac autonomic nerve dysfunction were related with ECG abnormalities at early withdrawal stage. With the improvement of ECG abnormalities after abstinence, these relationship became poorer. These results suggest ECG abnormalities in alcoholics are affected by several deterioration at early withdrawal stage.
AB - It is quite difficult to judge whether various ECG abnormalities in asymptomatic alcoholics reflect latent stage of alcoholic cardiomyopathy, because several deterioration observed at alcoholic withdrawal stage modify ECG findings. To assess the ECG abnormalities during withdrawal stage, we studied the consecutive changes of ECG abnormalities after abstinence in 48 asymptomatic alcoholics admitted within 48 hours of last drink. The incidence of high QRS voltage (Sv1+Rv6>36 mm, Sv1+Rv5>40 mm, and Sv2+Rv5> 45mm) were 25%, 10%, and 13%, QTc prolongation (QTc>0.43 sec), 71%, 27%, and 15% on admission, 7th, and 30th hospital day, respectively. The consecutive changes of their correlations with drinking profile, electrolyte imbalance, blood pressure, heart rate, cardiac autonomic nerve dysfunction assessed by heart rate variability were studied by linear regression analyses. Heavy daily alcohol consumption, electrolyte imbalance, cardiac autonomic nerve dysfunction were related with ECG abnormalities at early withdrawal stage. With the improvement of ECG abnormalities after abstinence, these relationship became poorer. These results suggest ECG abnormalities in alcoholics are affected by several deterioration at early withdrawal stage.
KW - alcoholism
KW - autonomic nervous disturbance
KW - electrocardiogram
KW - withdrawal state
UR - http://www.scopus.com/inward/record.url?scp=85004262742&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85004262742&partnerID=8YFLogxK
U2 - 10.11261/iryo1946.44.222
DO - 10.11261/iryo1946.44.222
M3 - Article
AN - SCOPUS:85004262742
VL - 44
SP - 222
EP - 226
JO - IRYO - Japanese Journal of National Medical Services
JF - IRYO - Japanese Journal of National Medical Services
SN - 0021-1699
IS - 3
ER -