The contribution of blood oxygenation changes in the capillary bed and a small blood vessel on the brain surface to NIRS signals

Kazushi Honjyo, Eiji Okada, Atsushi Maki, David T. Delpy

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

Changes in the optical density of the brain measured by near infrared spectroscopy (NIRS) instruments reflect blood oxygenation changes in the various blood vessels in the brain. Light propagation in a model of the head predicted by a Monte Carlo simulation has been used to estimate the contribution of blood oxygenation change in the capillary bed and in larger blood vessels in the brain to NIRS signal. Results show that the effective partial path length in the brain tissue is much longer than that in the blood vessel on the brain surface and that blood oxygenation change in the capillary bed are me major contributors to the change in the NIRS signal.

Original languageEnglish
Title of host publicationBiomedical Optical Spectroscopy and Diagnostics, BOSD 2000
PublisherOptica Publishing Group (formerly OSA)
Pages289-291
Number of pages3
ISBN (Electronic)9781557528209
Publication statusPublished - 2000
EventBiomedical Optical Spectroscopy and Diagnostics, BOSD 2000 - Miami Beach, United States
Duration: 2000 Apr 2 → …

Publication series

NameOptics InfoBase Conference Papers

Conference

ConferenceBiomedical Optical Spectroscopy and Diagnostics, BOSD 2000
Country/TerritoryUnited States
CityMiami Beach
Period00/4/2 → …

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Mechanics of Materials

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