The fetal dermal but not loose fascial mesenchymal cells possess regenerative activity of dermal structure

Kazuo Kishi, Kenichi Katsube, Hiroko Satoh, Nobuaki Imanishi, Hideo Nakajima, Tatsuo Nakajima

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Fetal skin possesses a regenerative activity until certain developmental stages. However, the origin of cells that regenerate dermis after wounding has not been clarified yet. In the present study we located the origin of cells that reconstruct fetal dermal structure by histological examination and by marking cells in the loose fascia. Next we evaluated the regenerative activity of fetal dermal mesenchymal cells by cotransplanting with fetal epidermal cells onto the skin defect of scid mice. We conclude that fetal dermal mesenchymal cells but not loose fascial cells possess regenerative activity even on the environment in scid mice.

Original languageEnglish
Pages (from-to)709-714
Number of pages6
JournalCell Transplantation
Volume14
Issue number9
DOIs
Publication statusPublished - 2005 Dec 1

Keywords

  • Dermal
  • Fetal wound healing
  • Regeneration
  • Scid mouse

ASJC Scopus subject areas

  • Biomedical Engineering
  • Cell Biology
  • Transplantation

Fingerprint Dive into the research topics of 'The fetal dermal but not loose fascial mesenchymal cells possess regenerative activity of dermal structure'. Together they form a unique fingerprint.

  • Cite this