The first synthesis of both enantiomers of [α-2H]phenylacetic acid in high enantiomeric excess

K. Matoishi, S. Hanzawa, H. Kakidani, M. Suzuki, T. Sugai, H. Ohta

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Arylmalonate decarboxylase (EC. 4. 1. 1. 76) catalysed decarboxylation followed by enantioface-differentiating protonation of [α-2H]- and [α-1H]phenylmalonic acid in 1H2O and 2H2O respectively, gave highly enantiomerically enriched (R)- and (S)-[α-2H]phenylacetic acid in quantitative yields.

Original languageEnglish
Pages (from-to)1519-1520
Number of pages2
JournalChemical Communications
Issue number16
DOIs
Publication statusPublished - 2000 Aug 21

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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