The isolation and structures of euphoscopins a and b

Shosuke Yamamura, Seiji Kosemura, Shigeru Ohba, Masatoki Ito, Yoshihiko Saito

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

Two new toxic substances, euphoscopins A and B, have been isolated from the plant Euphorbia helioscopia L., and their absolute stereostructures also been elucidated on the basis of their spectral data coupled with an X-ray crystallographic analysis of the p-bromobenzoate readily obtained on treatment of euphoscopin A with p-bromobenzoyl chloride - pyridine. These antitumor substances belong to a group of jatrophone-type diterpenes.

Original languageEnglish
Pages (from-to)5315-5318
Number of pages4
JournalTetrahedron Letters
Volume22
Issue number52
DOIs
Publication statusPublished - 1981

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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