The isolation and structures of euphoscopins a and b

Shosuke Yamamura, Seiji Kosemura, Shigeru Ohba, Masatoki Ito, Yoshihiko Saito

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

Two new toxic substances, euphoscopins A and B, have been isolated from the plant Euphorbia helioscopia L., and their absolute stereostructures also been elucidated on the basis of their spectral data coupled with an X-ray crystallographic analysis of the p-bromobenzoate readily obtained on treatment of euphoscopin A with p-bromobenzoyl chloride - pyridine. These antitumor substances belong to a group of jatrophone-type diterpenes.

Original languageEnglish
Pages (from-to)5315-5318
Number of pages4
JournalTetrahedron Letters
Volume22
Issue number52
DOIs
Publication statusPublished - 1981

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Bromobenzoates
Euphorbia
Diterpenes
Poisons
Chlorides
X-Rays
X rays
jatrophone
pyridine

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

The isolation and structures of euphoscopins a and b. / Yamamura, Shosuke; Kosemura, Seiji; Ohba, Shigeru; Ito, Masatoki; Saito, Yoshihiko.

In: Tetrahedron Letters, Vol. 22, No. 52, 1981, p. 5315-5318.

Research output: Contribution to journalArticle

Yamamura, Shosuke ; Kosemura, Seiji ; Ohba, Shigeru ; Ito, Masatoki ; Saito, Yoshihiko. / The isolation and structures of euphoscopins a and b. In: Tetrahedron Letters. 1981 ; Vol. 22, No. 52. pp. 5315-5318.
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