The Japan Marrow Donor Program, 25 years of experience in achieving 20,000 bone marrow transplantations: organization structure, activity, and financial basis

on behalf of JMDP

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

The Japan Marrow Donor Program (JMDP), established in 1991, has continued to grow in its capacity to facilitate unrelated bone marrow (BMT) and peripheral blood stem cell transplantation (PBSCT) for the past 25 years in Japan. The current donor pool is 463,465 (as of 31 December 2016) and 20,237 transplants were performed with the help of the Japanese Red Cross, government, and supporters. As JMDP introduced PBSCT in 2010, the vast majority of transplants are BMT. All donors are fully typed for HLA-A, B, C, and DR. The peak age of registered donors is around 40 years. The 8/8 HLA-matched donors are found in our registry for 96% of the patients and 54% of the patients receive a transplant. The median time between the initiation of donor search and the transplantation is approximately 122 days. The median interval between the initiation of donor search and identification of the first potential donor is 40 days. The most common diseases for which unrelated BMT/PBSCT is indicated are acute myelogenous leukemia (AML), acute lymphocytic leukemia (ALL), myelodysplastic syndrome (MDS), and malignant lymphoma. In recent years we have seen a marked increase in elderly patients who received BMT.

Original languageEnglish
Pages (from-to)1-8
Number of pages8
JournalBone Marrow Transplantation
DOIs
Publication statusAccepted/In press - 2018 Jan 24
Externally publishedYes

Fingerprint

Bone Marrow Transplantation
Japan
Bone Marrow
Tissue Donors
Organizations
Peripheral Blood Stem Cell Transplantation
Transplants
Red Cross
HLA-A Antigens
HLA-B Antigens
Myelodysplastic Syndromes
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Acute Myeloid Leukemia
Registries
Lymphoma
Transplantation

ASJC Scopus subject areas

  • Hematology
  • Transplantation

Cite this

@article{806da5716db44611a802101a72ac1712,
title = "The Japan Marrow Donor Program, 25 years of experience in achieving 20,000 bone marrow transplantations: organization structure, activity, and financial basis",
abstract = "The Japan Marrow Donor Program (JMDP), established in 1991, has continued to grow in its capacity to facilitate unrelated bone marrow (BMT) and peripheral blood stem cell transplantation (PBSCT) for the past 25 years in Japan. The current donor pool is 463,465 (as of 31 December 2016) and 20,237 transplants were performed with the help of the Japanese Red Cross, government, and supporters. As JMDP introduced PBSCT in 2010, the vast majority of transplants are BMT. All donors are fully typed for HLA-A, B, C, and DR. The peak age of registered donors is around 40 years. The 8/8 HLA-matched donors are found in our registry for 96{\%} of the patients and 54{\%} of the patients receive a transplant. The median time between the initiation of donor search and the transplantation is approximately 122 days. The median interval between the initiation of donor search and identification of the first potential donor is 40 days. The most common diseases for which unrelated BMT/PBSCT is indicated are acute myelogenous leukemia (AML), acute lymphocytic leukemia (ALL), myelodysplastic syndrome (MDS), and malignant lymphoma. In recent years we have seen a marked increase in elderly patients who received BMT.",
author = "{on behalf of JMDP} and Hidehiko Saito and Masaharu Ito and Shunichi Kato and Yoshihisa Kodera and Shinichiro Okamoto and Shuichi Taniguchi and Minoko Takanashi and Heiwa Kanamori and Toru Masaoka and Fumimaro Takaku",
year = "2018",
month = "1",
day = "24",
doi = "10.1038/s41409-017-0084-2",
language = "English",
pages = "1--8",
journal = "Bone Marrow Transplantation",
issn = "0268-3369",
publisher = "Nature Publishing Group",

}

TY - JOUR

T1 - The Japan Marrow Donor Program, 25 years of experience in achieving 20,000 bone marrow transplantations

T2 - organization structure, activity, and financial basis

AU - on behalf of JMDP

AU - Saito, Hidehiko

AU - Ito, Masaharu

AU - Kato, Shunichi

AU - Kodera, Yoshihisa

AU - Okamoto, Shinichiro

AU - Taniguchi, Shuichi

AU - Takanashi, Minoko

AU - Kanamori, Heiwa

AU - Masaoka, Toru

AU - Takaku, Fumimaro

PY - 2018/1/24

Y1 - 2018/1/24

N2 - The Japan Marrow Donor Program (JMDP), established in 1991, has continued to grow in its capacity to facilitate unrelated bone marrow (BMT) and peripheral blood stem cell transplantation (PBSCT) for the past 25 years in Japan. The current donor pool is 463,465 (as of 31 December 2016) and 20,237 transplants were performed with the help of the Japanese Red Cross, government, and supporters. As JMDP introduced PBSCT in 2010, the vast majority of transplants are BMT. All donors are fully typed for HLA-A, B, C, and DR. The peak age of registered donors is around 40 years. The 8/8 HLA-matched donors are found in our registry for 96% of the patients and 54% of the patients receive a transplant. The median time between the initiation of donor search and the transplantation is approximately 122 days. The median interval between the initiation of donor search and identification of the first potential donor is 40 days. The most common diseases for which unrelated BMT/PBSCT is indicated are acute myelogenous leukemia (AML), acute lymphocytic leukemia (ALL), myelodysplastic syndrome (MDS), and malignant lymphoma. In recent years we have seen a marked increase in elderly patients who received BMT.

AB - The Japan Marrow Donor Program (JMDP), established in 1991, has continued to grow in its capacity to facilitate unrelated bone marrow (BMT) and peripheral blood stem cell transplantation (PBSCT) for the past 25 years in Japan. The current donor pool is 463,465 (as of 31 December 2016) and 20,237 transplants were performed with the help of the Japanese Red Cross, government, and supporters. As JMDP introduced PBSCT in 2010, the vast majority of transplants are BMT. All donors are fully typed for HLA-A, B, C, and DR. The peak age of registered donors is around 40 years. The 8/8 HLA-matched donors are found in our registry for 96% of the patients and 54% of the patients receive a transplant. The median time between the initiation of donor search and the transplantation is approximately 122 days. The median interval between the initiation of donor search and identification of the first potential donor is 40 days. The most common diseases for which unrelated BMT/PBSCT is indicated are acute myelogenous leukemia (AML), acute lymphocytic leukemia (ALL), myelodysplastic syndrome (MDS), and malignant lymphoma. In recent years we have seen a marked increase in elderly patients who received BMT.

UR - http://www.scopus.com/inward/record.url?scp=85040905327&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85040905327&partnerID=8YFLogxK

U2 - 10.1038/s41409-017-0084-2

DO - 10.1038/s41409-017-0084-2

M3 - Article

C2 - 29367710

AN - SCOPUS:85040905327

SP - 1

EP - 8

JO - Bone Marrow Transplantation

JF - Bone Marrow Transplantation

SN - 0268-3369

ER -