The laser driven heating balloon catheter: Vessel dilatation characteristics

Natsumi Shimazaki, Go Mizukami, Hisako Tokunaga, Kenji Kaneko, Tsunenori Arai

Research output: Chapter in Book/Report/Conference proceedingConference contribution

11 Citations (Scopus)

Abstract

We studied on the dilatation characteristics of our new angioplasty, photo-thermo dynamic balloon (PTDB) angioplasty, which provides short-term heating (<15s, 50-70°C) dilatation by the combination of laser heat generator and fluid perfusion. In this study, we employed the ex vivo experiments to demonstrate the feasibility of our PTDB angioplasty with extracted porcine carotid artery. Balloon temperature and heating duration were easily controlled with the laser power and irradiation duration. Arterial dilatation was performed with the prototype PTDB catheter (3mm in diameter) ex vivo, sufficient dilation was attained with low dilatation pressure (2atm) that is lower than the limit pressure of elastic region (8atm in this case). The principal of our PTDB angioplasty that was based on the experimental results was dilatation in elastic region, while traditional POBA was accompanied with plastic deformation of artery. It is predicted that successful way of PTDB dilatation was attributed to collagen softening. Collagen coagulation and/or restructure after the heating dilatation might suspend the dilated arterial lumen. We demonstrated the feasibility of our PTDB angioplasty. We think collagen denaturation degree may be the important factor in this methodology.

Original languageEnglish
Title of host publicationProceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08
Pages3661-3663
Number of pages3
Publication statusPublished - 2008 Dec 1
Event30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - Vancouver, BC, Canada
Duration: 2008 Aug 202008 Aug 25

Publication series

NameProceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology"

Other

Other30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08
CountryCanada
CityVancouver, BC
Period08/8/2008/8/25

ASJC Scopus subject areas

  • Computer Vision and Pattern Recognition
  • Signal Processing
  • Biomedical Engineering
  • Health Informatics

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  • Cite this

    Shimazaki, N., Mizukami, G., Tokunaga, H., Kaneko, K., & Arai, T. (2008). The laser driven heating balloon catheter: Vessel dilatation characteristics. In Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 (pp. 3661-3663). [4650001] (Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology").