The manners of aromatization of a new 10-membered ring 1,6-diyn-3-ene system under basic conditions

Kazunobu Toshima, Kazumi Ohta, Tatsuya Ohtake, Kuniaki Tatsuta

Research output: Contribution to journalArticle

36 Citations (Scopus)


Treatment of a novel 10-membered ring 1,6-diyn-3-ene compound 1 with alcoholic KOH solution gave istohiochromanol derivatives through a polar pathway. On the other hand, treatment of 1 with DBU in CCl4 afforded 8-chloroisothiochromane derivatives through a free radical pathway.

Original languageEnglish
Pages (from-to)391-394
Number of pages4
JournalTetrahedron Letters
Issue number3
Publication statusPublished - 1991 Jan 14


ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

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